Antonacci Rachele, Bellini Mariagrazia, Castelli Vito, Ciccarese Salvatrice, Massari Serafina
Department of Biology, University "Aldo Moro" of Bari, Bari, Italy.
Department of Biological and Environmental Science e Technologies, University of Salento, Lecce, Italy.
Data Brief. 2017 Aug 3;14:507-514. doi: 10.1016/j.dib.2017.08.002. eCollection 2017 Oct.
These data are presented in support of structural and evolutionary analysis of the published article entitled "The occurrence of three D-J-C clusters within the dromedary TRB locus highlights a shared evolution in Tylopoda, Ruminantia and Suina" (Antonacci et al., 2017) [1]. Here we describe the genomic structure and the gene content of the T cell receptor beta chain (TRB) locus in As in the other species of mammals, the general genomic organization of the dromedary TRB locus consists of a pool of TRBV genes located upstream of in tandem TRBD-J-C clusters, followed by a TRBV gene with an inverted transcriptional orientation. A peculiarity of the dromedary TRB locus structure is the presence of three TRBD-J-C clusters, which is a common feature of sheep, cattle and pig sequences.
这些数据是为支持题为《单峰骆驼TRB基因座内三个D-J-C簇的出现突显了偶蹄目、反刍亚目和猪形亚目的共同进化》（Antonacci等人，2017年）[1]的已发表文章的结构和进化分析而呈现的。在此，我们描述了单峰骆驼T细胞受体β链（TRB）基因座的基因组结构和基因内容。与其他哺乳动物物种一样，单峰骆驼TRB基因座的一般基因组组织由位于串联TRBD-J-C簇上游的一组TRBV基因组成，随后是一个转录方向倒置的TRBV基因。单峰骆驼TRB基因座结构的一个独特之处是存在三个TRBD-J-C簇，这是绵羊、牛和猪序列的一个共同特征。
