Department of Periodontology, School of Dentistry, Necmettin Erbakan University, Konya, Turkey.
Department of Medical Pathology, Bülent Ecevit University School of Medicine, Zonguldak, Turkey.
Clin Implant Dent Relat Res. 2017 Dec;19(6):1009-1014. doi: 10.1111/cid.12528. Epub 2017 Aug 30.
The objective of this study is to evaluate the effect of Platelet rich fibrin (PRF) treatment of maxillary sinus membrane perforation on bone formation and new vascular supply and the success of dental implant survival rate.
The dataset for this retrospective study consists of patients who received sinus augmentation using the lateral wall technique. A total of 16 patients (20 sinuses) the patients without sinus membrane perforation (10 maxiller sinus area with sinus floor augmentation) and with Schneiderian perforation (10 maxiller sinus area repairing with PRF and augmented sinus floor area) were included in this study. The bone height was measured by comparing the preoperative and postoperative dental CBCT scans. Histological sections were evaluated for possible vasculogenesis augmented sinuses area.
In both groups, it was observed that the possible vasculogenesis augmented sinuses area increased. Implant survival rates in both groups found that one hundred percent and any bone loss around implants were not observed. An apparent increase in alveolar bone height was observed and measured in CBCT scans.
PRF can be considered as an alternative material for repairing sinus perforations because it is fully autogenous and easy manipulated.
本研究旨在评估富血小板纤维蛋白（PRF）治疗上颌窦膜穿孔对骨形成和新血管供应的影响，以及种植牙存活率的成功。
本回顾性研究的数据集中包括接受经侧壁技术进行鼻窦增大的患者。共有 16 名患者（20 个鼻窦），其中无鼻窦膜穿孔（10 个上颌窦区进行鼻窦底增高术）和有 Schneiderian 穿孔（10 个上颌窦区用 PRF 修复和鼻窦底增高区）。通过比较术前和术后牙科 CBCT 扫描来测量骨高度。对可能的血管生成增强窦区的组织学切片进行评估。
在两组中，都观察到可能的血管生成增强窦区增加。两组的种植体存活率均为 100%，且未观察到种植体周围任何骨质丢失。在 CBCT 扫描中观察到并测量到牙槽骨高度明显增加。
PRF 可以被认为是修复鼻窦穿孔的一种替代材料，因为它是完全自体的，易于操作。
