Riaz Irbaz Bin, Khan Muhammad Shahzeb, Mazursky Konstantin, Husnain Muhammad, Anwer Faiz
Irbaz bin Riaz practices in the Department of Internal Medicine at the University of Arizona in Tucson. Muhammad Shahzeb Khan practices at Dow University of Health Sciences in Karachi, Pakistan. Konstantin Mazursky practices in the Department of Internal Medicine at the University of Arizona. Muhammad Husnain practices in the Division of Cardiovascular Diseases, Department of Medicine, at the University of Arizona. Faiz Anwer practices in the Division of Hematology, Oncology, Blood, and Marrow Transplantation, Department of Medicine, at the University of Arizona. The authors have disclosed no potential conflicts of interest, financial or otherwise.
JAAPA. 2017 Sep;30(9):27-29. doi: 10.1097/01.JAA.0000521135.38539.f4.
This article describes a 71-year-old man with right knee pain, prerenal azotemia, hypercalcemia, and a mass in the distal femur. Although testing, including bone marrow biopsy, initially ruled out myeloma, an open surgical biopsy eventually confirmed the diagnosis as lymphoma involving the bone with classic histologic findings of mature B-cell neoplasm of germinal cell origin.
本文描述了一名71岁男性，患有右膝疼痛、肾前性氮质血症、高钙血症以及股骨远端肿块。尽管包括骨髓活检在内的检查最初排除了骨髓瘤，但开放性手术活检最终确诊为淋巴瘤累及骨骼，具有生发细胞起源的成熟B细胞肿瘤的典型组织学表现。
