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纳洛西戈用于治疗阿片类药物引起的便秘。

Naloxegol for managing opioid-induced constipation.

作者信息

Shelton Krystal N, Clements Jennifer N

机构信息

At the time this article was written, Krystal N. Shelton was a doctor of pharmacy student in the Presbyterian College School of Pharmacy in Clinton, S.C. She is now a pharmacist at CVS Pharmacy. Jennifer N. Clements is an associate professor in the Department of Pharmacy Practice at Presbyterian College School of Pharmacy. The authors have disclosed no potential conflicts of interest, financial or otherwise.

出版信息

JAAPA. 2017 Sep;30(9):51-53. doi: 10.1097/01.JAA.0000522146.29435.c7.

DOI:10.1097/01.JAA.0000522146.29435.c7
PMID:28858018
Abstract

Naloxegol is a peripherally acting mu-opioid receptor antagonist for opioid-induced constipation in adults with chronic noncancer pain. This drug's once-daily oral formulation can be used as monotherapy and helps to decrease the constipating effects of opioid therapy; however, it has been associated with abdominal pain.

摘要

纳洛西戈是一种外周作用的μ-阿片受体拮抗剂,用于治疗患有慢性非癌性疼痛的成人的阿片类药物引起的便秘。这种药物每日一次的口服制剂可作为单一疗法使用,并有助于减轻阿片类药物治疗的便秘作用;然而,它与腹痛有关。

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