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显微镜辅助下颈椎前路椎间盘切除融合术联合经管状牵开器后路微创手术治疗多节段脊髓型颈椎病:一项回顾性研究

Microscope-assisted anterior cervical discectomy and fusion combined with posterior minimally invasive surgery through tubular retractors for multisegmental cervical spondylotic myelopathy: A retrospective study.

作者信息

Cai Ran-Ze, Wang Yin-Qing, Wang Rui, Wang Chun-Hua, Chen Chun-Mei

机构信息

Department of neurosurgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.

出版信息

Medicine (Baltimore). 2017 Sep;96(35):e7965. doi: 10.1097/MD.0000000000007965.

Abstract

This study aimed to investigate the clinical efficacy and outcome of combined microscope-assisted anterior cervical discectomy and fusion (ACDF) with posterior minimally invasive surgery through tubular retractors for patients with multisegmental cervical spondylotic myelopathy (MCSM).This retrospective study included 28 patients (19 males and 9 females) with multisegmental cervical spondylotic myelopathy, who underwent combined microscope-assisted ACDF with posterior minimally invasive surgery through tubular retractors in our single center between January 2012 and December 2016. The evaluated postoperative clinical outcomes were operation time, length of hospitalization, blood loss, levels of creatine phosphokinase isoenzyme MM (CPK-MM), Japanese Orthopedic Association (JOA) scores, visual analogue scale (VAS) scores, Cobb angle of C2-C7, and radiological assessments (included X-rays, computed tomography scans, and magnetic resonanceimaging images).The mean surgery time was 198.42 ± 17.53 minutes, the average hospitalization length of hospital was 7.59 ± 1.38 days, and the mean follow-up time was 13 ± 2.45 months. On average, about 36.42 ± 10.15 mL of blood was lost and CPK-MM increased to 331.75 ± 23.15 IU/mL postoperatively (P < .001). The mean modified JOA scores increased from 8.21 ± 0.69 preoperatively to 13.96 ± 1.57 postoperatively (P < .001), whereas the mean VAS scores decreased from 6.64 ± 1.28 preoperatively to 0.39 ± 0.50 postoperatively (P < .001). Cobb angle of C2-C7 increased from 13.86° ± 5.69° preoperatively to 14.10° ± 5.56° postoperatively (P = .16).In conclusion, combined microscope-assisted ACDF with posterior minimally invasive surgery through tubular retractors appears to be a safe and effective treatment for patients with MCSM.

摘要

本研究旨在探讨联合显微镜辅助下颈椎前路椎间盘切除融合术(ACDF)与后路经皮管状牵开器辅助微创手术治疗多节段脊髓型颈椎病(MCSM)患者的临床疗效及预后。本回顾性研究纳入了28例多节段脊髓型颈椎病患者(19例男性,9例女性),这些患者于2012年1月至2016年12月在我们单中心接受了联合显微镜辅助下ACDF与后路经皮管状牵开器辅助微创手术。评估的术后临床结局包括手术时间、住院时间、失血量、肌酸磷酸激酶同工酶MM(CPK-MM)水平、日本骨科协会(JOA)评分、视觉模拟量表(VAS)评分、C2-C7 Cobb角以及影像学评估(包括X线、计算机断层扫描和磁共振成像)。平均手术时间为198.42±17.53分钟,平均住院时间为7.59±1.38天,平均随访时间为13±2.45个月。平均失血量约为36.42±10.15 mL,术后CPK-MM升高至331.75±23.15 IU/mL(P<0.001)。平均改良JOA评分从术前的8.21±0.69提高到术后的13.96±1.57(P<0.001),而平均VAS评分从术前的6.64±1.28降至术后的0.39±0.50(P<0.001)。C2-C7 Cobb角从术前的13.86°±5.69°增加到术后的14.10°±5.56°(P = 0.16)。总之,联合显微镜辅助下ACDF与后路经皮管状牵开器辅助微创手术似乎是治疗MCSM患者的一种安全有效的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89f5/5585523/cd91d88cdd7e/medi-96-e7965-g001.jpg

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