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青春期前阴道出血的当前综述。

Current review of prepubertal vaginal bleeding.

作者信息

Dwiggins Maggie, Gomez-Lobo Veronica

机构信息

aOSF Saint Francis Medical Center, University of Illinois College of Medicine at Peoria, Peoria, IllinoisbMedstar Washington Hospital Center, Children's National Medical Center, Washington, District of Columbia, USA.

出版信息

Curr Opin Obstet Gynecol. 2017 Oct;29(5):322-327. doi: 10.1097/GCO.0000000000000398.

DOI:10.1097/GCO.0000000000000398
PMID:28858895
Abstract

PURPOSE OF REVIEW

Prepubertal vaginal bleeding raises many concerns and evaluation and diagnosis may prove difficult for many providers. We aim to provide a comprehensive review and recent updates for those practitioners who care for these patients.

RECENT FINDINGS

Prompt management in the case of prepubertal vaginal bleeding is indicated, especially to rule out malignancy or abuse. If a child is reluctant to undergo examination, or if the extent of injury or source of bleeding cannot be determined, examination under anesthesia and vaginoscopy is recommended. Use of vaginoscopy allows for clear visualization of the vagina and cervix without distorting hymenal anatomy, as well as diagnosis and removal of a foreign body and evaluation of mucosal damage caused. In the case of sexual abuse, providers specifically trained in pediatrics need to be present, and safety of the patient should always be ensured.

SUMMARY

Careful history taking and targeted examination may lead to diagnosis in the case of prepubertal vaginal bleeding. However, in more difficult cases, practitioners should not hesitate to examine a patient in the operating room using general anesthesia to elicit the cause. Although sexual abuse and malignancy are always on the differential, most causes of bleeding are benign and easily treated.

摘要

综述目的

青春期前阴道出血引发诸多担忧,许多医疗人员可能会觉得评估和诊断颇具难度。我们旨在为照料这些患者的从业者提供全面的综述及最新进展。

最新发现

青春期前阴道出血的情况需要及时处理,尤其要排除恶性肿瘤或虐待。如果患儿不愿接受检查,或者无法确定损伤程度或出血来源,建议在麻醉下进行检查及阴道镜检查。使用阴道镜能够清晰观察阴道和宫颈,而不会扭曲处女膜的解剖结构,还能诊断并取出异物,评估所造成的黏膜损伤。在性虐待的情况下,需要有经过儿科专门培训的医疗人员在场,并且始终要确保患者的安全。

总结

对于青春期前阴道出血的情况,仔细询问病史并进行针对性检查可能会得出诊断结果。然而,在更棘手的病例中,从业者应毫不犹豫地在手术室使用全身麻醉对患者进行检查以找出病因。虽然性虐待和恶性肿瘤始终是鉴别诊断的考虑因素,但大多数出血原因是良性的且易于治疗。

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1
Current review of prepubertal vaginal bleeding.青春期前阴道出血的当前综述。
Curr Opin Obstet Gynecol. 2017 Oct;29(5):322-327. doi: 10.1097/GCO.0000000000000398.
2
Vaginal bleeding in children: A retrospective audit at a tertiary paediatric gynaecology service.儿童阴道出血:三级儿科妇科服务机构的一项回顾性审计
J Paediatr Child Health. 2023 Apr;59(4):653-659. doi: 10.1111/jpc.16366. Epub 2023 Feb 7.
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[Genital hemorrhage in girls before puberty. Apropos of 33 cases].[青春期前女童生殖器出血。附33例报告]
Sem Hop. 1984 Apr 19;60(17):1195-9.
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Prepubertal Vaginal Bleeding: An Inpatient Series from a Single Center in Fujian China.青春期前阴道出血:来自中国福建单一中心的住院病例系列研究
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Evaluation of vaginal bleeding in the preadolescent child.青春期前儿童阴道出血的评估。
Semin Pediatr Surg. 1998 Feb;7(1):35-42. doi: 10.1016/s1055-8586(98)70004-6.
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Abnormal vaginal bleeding in the nonpregnant patient.非妊娠患者的异常阴道出血。
Emerg Med Clin North Am. 2003 Aug;21(3):751-72. doi: 10.1016/s0733-8627(03)00045-2.
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Vaginal bleeding in childhood: a review of 51 patients.
Br J Obstet Gynaecol. 1978 Oct;85(10):721-5. doi: 10.1111/j.1471-0528.1978.tb15590.x.
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Has this prepubertal girl been sexually abused?这个青春期前的女孩遭受过性虐待吗?
JAMA. 2008 Dec 17;300(23):2779-92. doi: 10.1001/jama.2008.827.
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Clinical Review: Prepubertal Bleeding.临床综述:青春期前出血。
J Pediatr Adolesc Gynecol. 2023 Oct;36(5):435-441. doi: 10.1016/j.jpag.2023.06.002. Epub 2023 Jun 9.
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Prepubertal girl with vaginal bleeding.青春期前女童出现阴道出血。
J Emerg Med. 2014 Jun;46(6):769-71. doi: 10.1016/j.jemermed.2013.11.075. Epub 2014 Feb 2.

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Small spherical foreign bodies in the genitourinary tract and their management.泌尿系统内的小球形异物及其处理。
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Gynecological Problems in Newborns and Infants.新生儿及婴儿的妇科问题
J Clin Med. 2021 Mar 4;10(5):1071. doi: 10.3390/jcm10051071.
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A Rare Cause of Hypovolemic Shock in Prepubertal Girl: Vaginal Leech Infestation.青春期前女孩低血容量性休克的罕见原因:阴道水蛭感染。
Case Rep Obstet Gynecol. 2019 Jun 27;2019:3459837. doi: 10.1155/2019/3459837. eCollection 2019.