Studies of the major DNA binding proteins of two bovine herpes mammillitis virus isolates.

Antigenic cross-reaction of the DNA-binding protein between herpes simplex virus type 2 (HSV-2) and two bovine herpes mammillitis virus (BHMV) isolates (BHM-1 and BHMV CSIRO 290) was demonstrated by indirect immunofluorescence. Southern blot analysis showed a region of homology between HSV-2 BglII O DNA (coding for the HSV-2 major DNA-binding protein) and BHMV XbaI DNA fragment N, suggesting a similar gene map unit position on both genomes.