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巨大肾积水:仍然是一个现实问题!

Giant hydronephrosis: still a reality!

作者信息

Kaura Kawaljit Singh, Kumar Manoj, Sokhal Ashok Kr, Gupta Ashok Kr, Purkait Bimalesh, Saini Durgesh, Sankhwar Satyanarayan

机构信息

Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India.

出版信息

Turk J Urol. 2017 Sep;43(3):337-344. doi: 10.5152/tud.2017.78379. Epub 2017 Aug 1.

Abstract

OBJECTIVE

Giant hydronephrosis (GH) is a rare entity in both developed and developing countries with less than 500 cases reported in the literature. Delayed diagnosis and management of GH, can result in long-term complications like hypertension, rupture of the kidney, renal failure and malignant change. We aim to highlight the importance of this often neglected entity and build a consensus for its early diagnosis and management.

MATERIAL AND METHODS

Patients with GH were thoroughly worked up, managed and followed up between June 2013 and December 2015 and epidemiologic, radiological, perioperative and follow-up data was recorded.

RESULTS

A total of 35 patients (adults and children) were reported. Flank pain in adults and abdominal lump in children were the most common clinical presentation. Percutaneous nephrostomy tube was placed in all patients and detailed work up was done to reach final diagnosis. Pelvi-ureteric junction obstruction (PUJO) was the final diagnosis in 32 patients (91.4%). Kidneys were non-functioning in 13 cases (37.1%) so nephrectomies were performed. Reduction pyeloplasty with nephropexy was done in 21 patients (60%) with 81% success and 23.1% complication rates.

CONCLUSION

GH requires early diagnosis and management to prevent higher nephrectomy rate along with poor success rate of conservative surgery like pyeloplasty.

摘要

目的

巨大肾积水(GH)在发达国家和发展中国家均属罕见病症,文献报道病例不足500例。GH诊断和治疗延误可导致高血压、肾破裂、肾衰竭及恶变等长期并发症。我们旨在强调这一常被忽视病症的重要性,并就其早期诊断和治疗达成共识。

材料与方法

2013年6月至2015年12月期间,对GH患者进行了全面检查、治疗及随访,并记录了流行病学、放射学、围手术期及随访数据。

结果

共报告35例患者(成人及儿童)。成人的胁腹痛和儿童的腹部肿块是最常见的临床表现。所有患者均置入经皮肾造瘘管,并进行详细检查以明确最终诊断。32例患者(91.4%)最终诊断为肾盂输尿管连接部梗阻(PUJO)。13例患者(37.1%)的肾脏无功能,因此进行了肾切除术。21例患者(60%)接受了肾盂成形术加肾固定术,成功率为81%,并发症发生率为23.1%。

结论

GH需要早期诊断和治疗,以防止肾切除率升高以及肾盂成形术等保守手术成功率低下。

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