Baumrucker C R, Stover R
Biol Neonate. 1987;51(6):340-5. doi: 10.1159/000242673.
gamma-Glutamyltransferase (D-gamma-glutamyl transpeptidase, EC 2.3.2.2) activity in rat placentae changes during gestation. The enzyme activity reaches a peak during the second trimester on a per gram of tissue basis and coincides with the greatest placental growth (hyperplasia) period. However, the enzyme activity on a per placenta basis shows two peak activity periods. One coincides with the peak of activity determined on a per gram basis. The second peak occurs in the third trimester and appears to coincide with the period of greatest fetal growth. The occurrence of these enzyme changes supports the concept of a developmental role for gamma-glutamyltransferase in providing amino acids from glutathione to the placenta and fetus.
大鼠胎盘组织中的γ-谷氨酰转移酶（D-γ-谷氨酰转肽酶，EC 2.3.2.2）活性在妊娠期间会发生变化。以每克组织计算，该酶活性在妊娠中期达到峰值，且与胎盘生长（增生）最旺盛的时期一致。然而，以每个胎盘计算，该酶活性出现两个峰值期。其中一个峰值与以每克计算所确定的活性峰值一致。第二个峰值出现在妊娠晚期，似乎与胎儿生长最旺盛的时期一致。这些酶活性变化的出现支持了γ-谷氨酰转移酶在从谷胱甘肽向胎盘和胎儿提供氨基酸方面具有发育作用这一概念。
