Yang Anthony, Barman Naman, Chin Edward, Herron Daniel, Arvelakis Antonios, LaPointe Rudow Dianne, Florman Sander S, Palese Michael A
Department of Urology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1272, New York, NY, 10022, USA.
Department of Surgery, Mount Sinai Medical Center, New York, NY, USA.
J Robot Surg. 2018 Jun;12(2):343-350. doi: 10.1007/s11701-017-0741-x. Epub 2017 Aug 31.
Safety is of utmost importance in live donor nephrectomies. In this study, we describe our initial experience with robot-assisted laparoscopic donor nephrectomy (RDN) in comparison with the standard laparoscopic donor nephrectomy (LDN). We retrospectively reviewed 95 patients who either underwent RDN or LDN performed by a single surgeon from 2011 to 2016 at a tertiary institution. Donor perioperative course and postoperative outcome along with recipient outcomes were compared. Of the 95 cases, 73 were classified as LDN and 22 were classified as RDN. There were no significant differences between the two groups in age, sex, BMI, race, and ASA status. Operative times (p < 0.001) were longer in the RDN group, but eventually approached LDN times. Warm ischemia (p = 0.002) and extraction times (p = 0.05) were also longer in the RDN cohort. The donor length of hospital stay, complication rates, and postoperative change in eGFR from baseline were similar in both cohorts up to 1 year. Recipient outcomes, including delayed graft function, graft failure, and renal function up to 1 year, were also comparable. In this study, we compared the longest postoperative course so far in both donors and recipients between RDN and LDN. Up to 1 year, RDN does not negatively impact outcomes. Proficiency with RDN also quickly improved to match LDN, making it a suitable procedure for newer surgeons.
在活体供肾肾切除术中,安全至关重要。在本研究中,我们描述了机器人辅助腹腔镜供肾肾切除术(RDN)与标准腹腔镜供肾肾切除术(LDN)相比的初步经验。我们回顾性分析了2011年至2016年在一家三级医疗机构由同一位外科医生实施RDN或LDN的95例患者。比较了供体围手术期过程、术后结果以及受体的结果。95例病例中,73例归类为LDN,22例归类为RDN。两组在年龄、性别、体重指数、种族和美国麻醉医师协会(ASA)分级方面无显著差异。RDN组的手术时间更长(p < 0.001),但最终接近LDN组的手术时间。RDN组的热缺血时间(p = 0.002)和取出时间(p = 0.05)也更长。两组供体住院时间、并发症发生率以及术后估算肾小球滤过率(eGFR)相对于基线的变化在1年内相似。受体的结果,包括移植肾功能延迟恢复、移植肾失功以及1年内的肾功能,也具有可比性。在本研究中,我们比较了RDN和LDN供体及受体迄今为止最长的术后病程。长达1年的时间里,RDN对结果没有负面影响。对RDN的熟练程度也迅速提高至与LDN相当,使其成为新外科医生的合适术式。