Tatsuoka Y, Riskind P N, Beal M F, Martin J B
Brain Res. 1987 May 12;411(1):200-3. doi: 10.1016/0006-8993(87)90702-5.
Somatostatin, neuropeptide Y and dopamine release from the conscious rat caudate nucleus were investigated using the push-pull perfusion method. Significant reductions in somatostatin and neuropeptide Y release coincided with increased dopamine release, suggesting that dopamine has an inhibitory effect on the release of both peptides. Changes in the levels of both peptides were positively correlated, consistent with their co-release from neuropeptide Y- and somatostatin-containing striatal neurons.
采用推挽式灌注法研究了清醒大鼠尾状核中生长抑素、神经肽Y和多巴胺的释放。生长抑素和神经肽Y释放的显著减少与多巴胺释放的增加同时出现，这表明多巴胺对这两种肽的释放具有抑制作用。两种肽水平的变化呈正相关，这与它们从含有神经肽Y和生长抑素的纹状体神经元中共同释放一致。
