Obata-Tsuto H L
Brain Res Bull. 1987 May;18(5):613-20. doi: 10.1016/0361-9230(87)90131-6.
The distribution and fine structure of somatostatin-like immunoreactive neurons in rat hippocampus and gyrus dentatus were investigated by light and electron microscopic immunocytochemistry. Somatostatin-like immunoreactive neuronal perikarya and fibers could be visualized by using modified PAP immunocytochemistry. Immunoreactive neurons were selectively localized in the stratum orience of the hippocampus and hilar region of the gyrus dentatus, however, immunoreactive neurons were also sparsely observed throughout hippocampal formation. Somatostatin-like immunoreactive varicosities were abundantly distributed in the stratum pyramidale and some of them were considered to terminate on the pyramidal cells. Somatostatin-like immunoreactive neurons in the hippocampal formation generally contained many mitochondria, well-developed rough surfaced endoplasmic reticulum (rER), polysomes and some dense granules. Immunoreactivity was observed especially in the dense granules and membrane of rER. Pre- and post-synaptic elements of somatostatin-like immunoreactive neurons were detected throughout the hippocampal formation.
采用光镜和电镜免疫细胞化学方法，对大鼠海马和齿状回中生长抑素样免疫反应性神经元的分布及精细结构进行了研究。使用改良的PAP免疫细胞化学方法可观察到生长抑素样免疫反应性神经元胞体和纤维。免疫反应性神经元选择性地定位于海马的定向层和齿状回的门区，然而，在整个海马结构中也稀疏地观察到免疫反应性神经元。生长抑素样免疫反应性膨体大量分布于锥体细胞层，其中一些被认为终止于锥体细胞。海马结构中的生长抑素样免疫反应性神经元通常含有许多线粒体、发育良好的粗面内质网（rER）、多核糖体和一些致密颗粒。免疫反应性尤其在致密颗粒和rER膜中观察到。在整个海马结构中均检测到生长抑素样免疫反应性神经元的突触前和突触后成分。
