Tian Changwei, Xu Shuang, Wang Hua, Wang Wenming, Shen Hui
a Department of Acute Infectious Disease Control and School Health , Kunshan Centers for Disease Control and Prevention , Suzhou , Jiangsu , PR China.
b Department of School Health , Suzhou Centers for Disease Control and Prevention , Suzhou , Jiangsu , PR China.
Ann Hum Biol. 2017 Nov;44(7):644-647. doi: 10.1080/03014460.2017.1375557. Epub 2017 Sep 24.
Obesity is a well-established risk factor of elevated blood pressure; however, the relationships between normal weight status and the risk of hypertension and pre-hypertension are not clear.
The aim of this study is to describe the blood pressure effects of adiposity in non-overweight children.
In total, 588 097 non-overweight children aged 6-17 years were included from the National Surveys on Students' Constitution and Health. A non-linear relationship was found between age- and gender-standardised body mass index (BMI) z-score and pre-hypertension and hypertension, respectively. The odds ratios and 95% confidence intervals [ORs (95% CIs)] of pre-hypertension were 0.61 (0.59-0.63), 0.67 (0.65-0.68), 0.83 (0.83-0.84), 1.00 (reference), 1.13 (1.12-1.14), 1.18 (1.16-1.20) and 1.20 (1.18-1.22) for BMI z-scores of -1.2, -1.0, -0.5, 0 (reference), 0.5, 0.7 and 0.8, respectively. The ORs (95% CIs) of hypertension were 0.56 (0.54-0.58), 0.62 (0.61-0.64), 0.81 (0.80-0.82), 1.00 (reference), 1.17 (1.16-1.18), 1.23 (1.22-1.5) and 1.27 (1.24-1.29) for BMI z-scores of -1.2, -1.0, -0.5, 0 (reference), 0.5, 0.7 and 0.8, respectively. The above-mentioned associations were consistent in sub-group analysis by age, gender and height.
Non-linear relationships of BMI z-scores with pre-hypertension and hypertension were found in non-overweight children. Interventions to control blood pressure are also important in non-overweight children.
肥胖是血压升高的一个公认风险因素；然而，正常体重状态与高血压及高血压前期风险之间的关系尚不清楚。
本研究旨在描述非超重儿童肥胖对血压的影响。
本研究共纳入了来自全国学生体质与健康调研的588097名6至17岁的非超重儿童。年龄和性别标准化体重指数（BMI）z评分与高血压前期及高血压之间分别存在非线性关系。BMI z评分为-1.2、-1.0、-0.5、0（参照值）、0.5、0.7和0.8时，高血压前期的比值比及95%置信区间[ORs(95% CIs)]分别为0.61(0.59 - 0.63)、0.67(0.65 - 0.68)、0.83(0.83 - 0.84)、1.00（参照值）、1.13(1.12 - 1.14)、1.18(1.16 - 1.20)和1.20(1.18 - 1.22)。BMI z评分为-1.2、-1.0、-0.5、0（参照值）、0.5、0.7和0.8时，高血压的ORs(95% CIs)分别为0.56(0.54 - 0.58)、0.62(0.61 - 0.64)、0.81(0.8o - 0.82)、1.00（参照值）、1.17(1.16 - 1.18)、1.23(1.22 - 1.25)和1.27(1.24 - 1.29)。上述关联在按年龄、性别和身高进行的亚组分析中是一致的。
在非超重儿童中发现BMI z评分与高血压前期及高血压之间存在非线性关系。控制血压干预措施对非超重儿童也很重要。
