Vuillerot C, Marret S, Dinomais M
L'Escale médecine physique et réadaptation, hôpital Femme-Mère-Enfant, CHU de Lyon, 59, boulevard Pinel, Bron, F-69677 France; CNRS UMR 5558, laboratoire de biométrie et biologie évolutive, équipe Biostatistiques Santé, Pierre-Bénite, 69310 France; université de Lyon, Lyon, 69000 France.
Service de pédiatrie néonatale et réanimation - neuropédiatrie - centre de référence des troubles des apprentissages de l'enfant, hôpital Charles-Nicolle, CHU de Rouen, et IN5ERM (U1245), équipe 4 Neovasc, handicap périnatal, institut biomédical de recherche et d'innovation (RÎB), UFR de médecine pharmacie de Rouen, université de Normandie, France.
Arch Pediatr. 2017 Sep;24(9S):9S51-9S60. doi: 10.1016/S0929-693X(17)30332-9.
Neonatal Arterial Ischemic Stroke (NAIS) affects 6-17 newborns on 100 000-birth term neonates, most of these children keeping long-term motor and cognitive impairments. Based on a literature review, the objectives of this paper are to describe motor and cognitive outcomes after a NAIS and to propose a consensual monitoring of these children to improve their management. About 30 % of children after a NAIS will develop a unilateral cerebral palsy requiring a management by a team with expertise in physical medicine and rehabilitation. Unlike adults, especially after a left NAIS, children will not present aphasia but between 50 and 90 % will present disorders of speech and language in expression and/or reception. After NAIS, the global intellectual efficiency is usually preserved except when the size of the lesion is very important or when severe epilepsy occurs. Several studies are also in favor of vulnerability in visuospatial functions. To quantify impairments, activity limitations and participation restrictions resulting from this NAIS, early and at least yearly evaluations with reliable tools must be carried out systematically until puberty. A multidisciplinary team with a longitudinal follow-up, in all the different developmental dimensions, must conduct these evaluations in term of motor skills, cognitive impairment, behavior, autonomy, quality of life, and participation. Consequences on family functioning need to be evaluate in order to help children and family coping with this event.
新生儿动脉缺血性卒中(NAIS)在每10万名足月新生儿中影响6 - 17名新生儿,这些儿童中的大多数存在长期运动和认知障碍。基于文献综述,本文的目的是描述NAIS后的运动和认知结果,并提出对这些儿童进行共识性监测以改善其管理。约30%的NAIS患儿会发展为单侧脑瘫,需要由物理医学与康复专业团队进行管理。与成人不同,尤其是左侧NAIS后,儿童不会出现失语症,但50%至90%的儿童会出现表达和/或接受方面的言语和语言障碍。NAIS后,除了病变范围非常大或发生严重癫痫的情况外,整体智力效率通常得以保留。多项研究也支持视觉空间功能存在易损性。为了量化NAIS导致的损伤、活动受限和参与限制,必须在青春期前系统地使用可靠工具进行早期评估,且至少每年评估一次。一个多学科团队必须在运动技能、认知障碍、行为、自主性、生活质量和参与等所有不同发育维度上进行纵向随访,开展这些评估。需要评估对家庭功能的影响,以帮助儿童和家庭应对这一事件。