正电子发射断层显像/计算机断层扫描与精准医学：食管癌
PET/Computed Tomography Scanning and Precision Medicine: Esophageal Cancer.
作者信息
Goel Reema, Subramaniam Rathan M, Wachsmann Jason W
机构信息
Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8896, USA.
Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8896, USA; Department of Clinical Sciences, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8896, USA; Department of Biomedical Engineering, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8896, USA; Advanced Imaging Research Center, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8896, USA; Harold C. Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8896, USA.
出版信息
PET Clin. 2017 Oct;12(4):373-391. doi: 10.1016/j.cpet.2017.05.001. Epub 2017 Jul 28.
Esophageal cancer commonly has a poor prognosis, which requires an accurate diagnosis and early treatment to improve outcome. Other modalities for staging, such as endoscopic ultrasound imaging and computed tomography (CT) scans, have a role in diagnosis and staging. However, PET with fluorine-18 fluoro-2-deoxy-d-glucose/CT (FDG PET/CT) scanning allows for improved detection of distant metastatic disease and can help to prevent unnecessary interventions that would increase morbidity. FDG PET/CT scanning is valuable in the neoadjuvant chemotherapy assessment and predicting survival outcomes subsequent to surgery. FDG PET/CT scanning detects recurrent disease and metastases in follow-up.
食管癌通常预后较差，这需要准确的诊断和早期治疗以改善预后。其他分期方式，如内镜超声成像和计算机断层扫描（CT），在诊断和分期中发挥作用。然而，氟-18氟代脱氧葡萄糖/CT（FDG PET/CT）扫描的正电子发射断层显像（PET）能够更好地检测远处转移性疾病，并有助于避免增加发病率的不必要干预。FDG PET/CT扫描在新辅助化疗评估以及预测手术后的生存结果方面具有重要价值。FDG PET/CT扫描可在随访中检测复发性疾病和转移灶。
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