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一项展示胸廓内动脉长度与自由血流之间定量关系的研究。

A Study Demonstrating the Quantitative Relationship Between Internal Thoracic Artery Length and Free Flow.

作者信息

Gode Safa, Sen Onur, Kadirogulları Ersin, Reyhancan Adem, Kyaruzi Mugisha, Satılmısoglu Muhammet Hulusi, Erkanlı Korhan

机构信息

Departments of Cardiovascular Surgery, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.

Departments of Cardiovascular Surgery, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.

出版信息

Heart Lung Circ. 2018 Jul;27(7):872-877. doi: 10.1016/j.hlc.2017.07.006. Epub 2017 Aug 9.

Abstract

BACKGROUND

The left internal thoracic artery (LITA) is the most commonly used arterial bypass conduit in coronary artery bypass graft (CABG) patients and inadequate LITA flow can result in an increase in morbidity and mortality. In this study, we evaluated the effect of excision of the distal spasmodic segment of the LITA on the free flow in CABG patients.

METHODS

This study consisted of 47 patients who underwent elective CABG performed with or without other cardiac surgery, between July 2015 and December 2015. Excised LITA length was shorter than 15mm in group 1, between 15mm and 30mm in group 2 and longer than 30mm in group 3. Left ITA free flow was measured for 60seconds into a container before and after the distal LITA excision. The inter-measurement differences were calculated for the three groups. Thereafter, the comparison was performed in terms of free flow difference amongst the three groups.

RESULTS

The mean difference of LITA free flow was 27.6±22.7ml/minute in group 1, 35.4±26.7ml/minute in group 2, and 52.6±26.1ml/minute in group 3. There were significant differences in terms of free flow difference between the groups (p=0.008). Also, differences were statistically significant in group 1 versus group 3 (p=0.003) and group 2 versus group 3 (p=0.038) in the intergroup comparisons.

CONCLUSIONS

The distal part of the LITA has more spasmodic potential than other segments. This spasm may result in low flow of LITA grafts. Therefore, an as long as possible excision of the distal LITA segment may be required to avoid the spasmodic effect.

摘要

背景

左乳内动脉(LITA)是冠状动脉旁路移植术(CABG)患者中最常用的动脉搭桥管道,LITA血流不足可导致发病率和死亡率增加。在本研究中,我们评估了切除LITA远端痉挛段对CABG患者自由血流的影响。

方法

本研究纳入了2015年7月至2015年12月期间接受择期CABG手术(无论是否合并其他心脏手术)的47例患者。第1组切除的LITA长度短于15mm,第2组在15mm至30mm之间,第3组长于30mm。在切除LITA远端前后,将左乳内动脉自由血流导入容器中测量60秒。计算三组测量值之间的差异。此后,对三组之间的自由血流差异进行比较。

结果

第1组LITA自由血流的平均差异为27.6±22.7ml/分钟,第2组为35.4±26.7ml/分钟,第3组为52.6±26.1ml/分钟。各组之间的自由血流差异有显著统计学意义(p = 0.008)。此外,在组间比较中,第1组与第3组(p = 0.003)和第2组与第3组(p = 0. – 038)之间的差异具有统计学意义。

结论

LITA的远端比其他节段具有更大的痉挛可能性。这种痉挛可能导致LITA移植物血流减少。因此,可能需要尽可能长地切除LITA远端节段以避免痉挛效应。

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