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三级护理医院中糖尿病足溃疡患者的临床和微生物学特征

Clinical and microbiological profile of diabetic foot ulcer patients in a tertiary care hospital.

作者信息

Kateel Ramya, Augustine Alfred J, Prabhu Shivananda, Ullal Sheetal, Pai Manohar, Adhikari Prabha

机构信息

Department of Medicine, Manipal University, Mangalore, India.

Department of Surgery, Manipal University, Mangalore, India.

出版信息

Diabetes Metab Syndr. 2018 Jan-Mar;12(1):27-30. doi: 10.1016/j.dsx.2017.08.008. Epub 2017 Aug 26.

Abstract

AIM

To evaluate the clinical and microbiological profile of diabetic foot ulcer patients admitted to a tertiary care hospital.

METHODOLOGY

This study recruited 120 diabetic foot ulcer patients of all grade. Their medical records were evaluated retrospectively.

RESULTS

We found that median age of patient was 60(52, 67.75) years. 68.3% of patients were males. Median duration of diabetes mellitus was 15(10, 20) years. Mean HbA1C and fasting glucose was 10.3±2.3 and 167.6±52.42 respectively. Neuropathy (35%) and peripheral vascular disease (23.3%) was major micro vascular and macro vascular complication associated. Different locations of ulcers were toe (23.3%), sole (20%), dorsum (18.3%), shin (16.6%), heel (13.3%), and ankle (8.3%). Bacterial infection was seen in 81.66% patients out of which 23.3% had poly microbial infection.

CONCLUSION

Diabetic foot ulcer patient had poor blood glucose control with elevated HbA1C and fasting blood glucose level. Neuropathy and peripheral vascular disease, hypertension were major complications. Staphylococcus aureus, Pseudomonas aeruginosa were common infecting bacteria.

摘要

目的

评估一家三级护理医院收治的糖尿病足溃疡患者的临床和微生物学特征。

方法

本研究招募了120例各分级的糖尿病足溃疡患者。对他们的病历进行回顾性评估。

结果

我们发现患者的中位年龄为60(52,67.75)岁。68.3%的患者为男性。糖尿病的中位病程为15(10,20)年。平均糖化血红蛋白和空腹血糖分别为10.3±2.3和167.6±52.42。神经病变(35%)和外周血管疾病(23.3%)是主要的微血管和大血管并发症。溃疡的不同部位为脚趾(23.3%)、足底(20%)、足背(18.3%)、小腿(16.6%)、足跟(13.3%)和脚踝(8.3%)。81.66%的患者存在细菌感染,其中23.3%为多重微生物感染。

结论

糖尿病足溃疡患者血糖控制不佳,糖化血红蛋白和空腹血糖水平升高。神经病变、外周血管疾病、高血压是主要并发症。金黄色葡萄球菌、铜绿假单胞菌是常见的感染细菌。

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