Bunck Alexander C, Dos Santos Daniel Pinto, Chang De-Hua, Reiser Marcel, Pfister David, Bunck Anne, Drzezga Alexander, Maintz David, Schmidt Matthias
Department of Radiology, University Hospital of Cologne, Cologne, Germany.
Practice for Oncology and Hematology, Cologne, Germany.
Case Rep Oncol. 2017 Jul 11;10(2):627-633. doi: 10.1159/000478004. eCollection 2017 May-Aug.
Prostate cancer is the most common solid tumor malignancy worldwide with an estimated 180,000 new cases of prostate cancer and 26,000 deaths in the USA in 2016. Although significant advances in the treatment of prostate cancer have recently been made, the treatment of metastatic disease remains a challenge. With visceral metastases marking more advanced tumor stages, liver involvement is associated with the worst prognosis. So far, no locoregional treatment regimens for the management of liver metastases of prostatic cancer exist. Herein, we report for the first time a successful treatment of hepatic metastases of prostatic cancer using radioembolization with selective intra-arterial administration of Yttrium-90 resin microspheres.
前列腺癌是全球最常见的实体瘤恶性肿瘤，2016年美国估计有18万例新的前列腺癌病例和2.6万例死亡。尽管近年来前列腺癌的治疗取得了重大进展，但转移性疾病的治疗仍然是一个挑战。内脏转移标志着肿瘤分期更晚，肝脏受累与最差的预后相关。到目前为止，尚无用于治疗前列腺癌肝转移的局部区域治疗方案。在此，我们首次报告了使用钇-90树脂微球选择性动脉内给药进行放射性栓塞成功治疗前列腺癌肝转移的病例。
