Kröner Paul Thomas, Sancar Aytekin, Fry Lucia C, Neumann Helmut, Mönkemüller Klaus
Basil I. Hirschowitz Endoscopic Center of Excellence, Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, USA.
Division of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University, Magdeburg, Germany.
GE Port J Gastroenterol. 2015 Jul 2;22(4):137-142. doi: 10.1016/j.jpge.2015.04.005. eCollection 2015 Jul-Aug.
There are only two single case reports describing double-balloon enteroscopy (DBE)-assisted endoscopic mucosal resection (EMR) of the jejunum. The aim of this case series was to evaluate the feasibility and utility of DBE-assisted EMR in patients with familial and non-familial jejunal polyps.
Observational, open-label, retrospective, single-arm case series in two hospitals.
Eight patients underwent DBE assisted jejunal EMR. Median age of patients was 42 years (range 24-62 years), male: female ratio 1.5:1. DBE was done through the antegrade (i.e. oral) route in all patients. Four patients had FAP; two had Peutz-Jeghers syndrome, one had a sporadic adenoma and one had a bleeding jejunal polyp, which on histological examination turned out to be lipoma. 3/8 underwent piece-meal EMR. No immediate adverse events occurred.
This is the first case series presenting the technical details, feasibility and outcomes of EMR of the small bowel. EMR of the jejunum is feasible and safe during DBE.
仅有两篇单病例报告描述了双气囊小肠镜（DBE）辅助下的空肠内镜黏膜切除术（EMR）。本病例系列的目的是评估DBE辅助EMR在家族性和非家族性空肠息肉患者中的可行性和实用性。
在两家医院进行的观察性、开放标签、回顾性、单臂病例系列研究。
8例患者接受了DBE辅助的空肠EMR。患者的中位年龄为42岁（范围24 - 62岁），男女比例为1.5:1。所有患者均通过顺行（即经口）途径进行DBE。4例患者患有家族性腺瘤性息肉病（FAP）；2例患有黑斑息肉综合征，1例患有散发性腺瘤，1例患有出血性空肠息肉，经组织学检查为脂肪瘤。8例中有3例接受了分片式EMR。未发生即刻不良事件。
这是首个展示小肠EMR技术细节、可行性和结果的病例系列。在DBE期间，空肠EMR是可行且安全的。
