Bech Sára, Haugbøl Steven, Winge Kristian
Ugeskr Laeger. 2017 Aug 14;179(33).
Parkinsonism (PD) is the clinical syndrome of bradykinesia combined with rigidity and/or tremor at rest. These are the defining characteristics of PD, but they are present in many other diseases of the brain. The most frequent differential diagnosis of PD are the atypical parkinsonian syndromes and the conditions presenting with mainly lower body parkinsonism. Discrimination between these can be challenging, especially at early stages of the disease, but nevertheless of utmost importance, because treatment and prognosis vary. Diagnoses are clinical, as disease-specific biomarkers are still lacking.
帕金森病（PD）是一种临床综合征，其特征为运动迟缓，并伴有静止性强直和/或震颤。这些是帕金森病的典型特征，但也见于许多其他脑部疾病。帕金森病最常见的鉴别诊断是非典型帕金森综合征以及主要表现为下肢帕金森症状的疾病。区分这些疾病可能具有挑战性，尤其是在疾病早期，但这仍然至关重要，因为治疗方法和预后各不相同。由于仍缺乏疾病特异性生物标志物，诊断主要依靠临床症状。
