[谷氨酸二乙酯对鳐鱼罗伦瓮突触过程的影响分析]
[Analysis of the effect of glutamic acid diethyl ester on synaptic processes in the ampullae of Lorenzini of the skate].
作者信息
Akoev G N, Andrianov Iu N, Sherman N O
出版信息
Neirofiziologiia. 1987;19(3):323-7.
PMID:2886931
Abstract
The effects of glutamic acid diethylester (GDEE) on the electrical activity of the ampullae of Lorenzini were studied in skates. GDEE (10(-6)-10(-4) M) caused a decrease in frequency of afferent discharges in all receptors under study. GDEE also reversibly blocked the effects of excitatory amino acids (L-glutamate and L-aspartate). The results suggest that L-glutamate or related substance is likely to be the synaptic transmitter in the ampullae of Lorenzini.
摘要
在鳐鱼中研究了谷氨酸二乙酯（GDEE）对洛伦兹壶腹电活动的影响。GDEE（10⁻⁶ - 10⁻⁴ M）使所有研究中的感受器传入放电频率降低。GDEE还可逆地阻断了兴奋性氨基酸（L-谷氨酸和L-天冬氨酸）的作用。结果表明，L-谷氨酸或相关物质可能是洛伦兹壶腹的突触递质。
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