Shieff C, Nashold B S
Neurol Res. 1987 Jun;9(2):101-4. doi: 10.1080/01616412.1987.11739778.
Forty years after its first reported use, stereotactic mesencephalic tractotomy remains effective in relieving thalamic pain. Twenty seven patients suffering central pain following cerebrovascular accidents were treated by this operation and twenty four were reviewed: sixteen (66.7%) reported long term relief. Fourteen underwent surgery at the original 'superior colliculus' target, nine out of twelve (75%) reporting significant relief. Thirteen had surgery at a revised 'inferior colliculus' target, seven out of twelve (58.3%) obtaining relief. Postoperative disorders of ocular movement were reduced from 83.3% to 20%, and significant problems of binocular vision from 50% to nil. The mortality rate was 7.4%.
在首次报道使用立体定向中脑束切断术40年后，该手术在缓解丘脑疼痛方面仍然有效。27例脑血管意外后出现中枢性疼痛的患者接受了该手术治疗，其中24例接受了复查：16例（66.7%）报告长期疼痛缓解。14例在最初的“上丘”靶点接受手术，12例中有9例（75%）报告疼痛显著缓解。13例在修订后的“下丘”靶点接受手术，12例中有7例（58.3%）疼痛得到缓解。术后眼球运动障碍从83.3%降至20%，双眼视力严重问题从50%降至零。死亡率为7.4%。
