Tuning polypeptide-based micellar carrier for efficient combination therapy of ErbB2-positive breast cancer.
作者信息
Soni Kruti S, Lei Fan, Desale Swapnil S, Marky Luis A, Cohen Samuel M, Bronich Tatiana K
机构信息
Department of Pharmaceutical Sciences, Center for Drug Delivery and Nanomedicine, College of Pharmacy, University of Nebraska Medical Center, 985830 Nebraska Medical Center, Omaha, NE 68198-5830, USA.
Department of Pharmaceutical Sciences, Center for Drug Delivery and Nanomedicine, College of Pharmacy, University of Nebraska Medical Center, 985830 Nebraska Medical Center, Omaha, NE 68198-5830, USA; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 985950 Nebraska Medical Center, Omaha, NE 68198-5950, USA.
出版信息
J Control Release. 2017 Oct 28;264:276-287. doi: 10.1016/j.jconrel.2017.08.038. Epub 2017 Sep 11.
Abstract
摘要
相似文献
1
Tuning polypeptide-based micellar carrier for efficient combination therapy of ErbB2-positive breast cancer.用于ErbB2阳性乳腺癌高效联合治疗的基于多肽的胶束载体的优化
J Control Release. 2017 Oct 28;264:276-287. doi: 10.1016/j.jconrel.2017.08.038. Epub 2017 Sep 11.
2
A novel combined micellar system of lapatinib and Paclitaxel with enhanced antineoplastic effect against human epidermal growth factor receptor-2 positive breast tumor in vitro.一种新型的拉帕替尼和紫杉醇联合胶束系统，在体外对人表皮生长因子受体2阳性乳腺肿瘤具有增强的抗肿瘤作用。
J Pharm Sci. 2015 Jan;104(1):165-77. doi: 10.1002/jps.24234. Epub 2014 Nov 24.
3
Thermosensitive poly-(d,l-lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly-(d,l-lactide-co-glycolide) hydrogels for multi-drug delivery.用于多药物递送的热敏聚（d，l-丙交酯-共-乙交酯）-嵌段-聚（乙二醇）-嵌段-聚（d，l-丙交酯-共-乙交酯）水凝胶
J Drug Target. 2014 Aug;22(7):669-77. doi: 10.3109/1061186X.2014.931406. Epub 2014 Jun 25.
4
Polypeptide-based nanogels co-encapsulating a synergistic combination of doxorubicin with 17-AAG show potent anti-tumor activity in ErbB2-driven breast cancer models.共封装阿霉素与17-AAG协同组合的基于多肽的纳米凝胶在ErbB2驱动的乳腺癌模型中显示出强大的抗肿瘤活性。
J Control Release. 2015 Jun 28;208:59-66. doi: 10.1016/j.jconrel.2015.02.001. Epub 2015 Feb 3.
5
Multi-drug delivery to tumor cells via micellar nanocarriers.通过胶束纳米载体向肿瘤细胞递药。
Int J Pharm. 2011 Oct 31;419(1-2):281-6. doi: 10.1016/j.ijpharm.2011.07.033. Epub 2011 Jul 27.
6
Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non-covalent association with anti-tumor antibodies.利用脂质体与抗肿瘤抗体非共价结合的方式进行特定的药物递送，能够有效地诱导人乳腺癌肿瘤消退。
J Nanobiotechnology. 2019 Feb 6;17(1):25. doi: 10.1186/s12951-019-0457-3.
7
Design and evaluation of micellar nanocarriers for 17-allyamino-17-demethoxygeldanamycin (17-AAG).胶束纳米载体的设计与评价用于 17-烯丙氨基-17-去甲氧基格尔德霉素（17-AAG）。
Int J Pharm. 2010 Jun 15;392(1-2):170-7. doi: 10.1016/j.ijpharm.2010.03.056. Epub 2010 Apr 2.
8
Combined delivery of paclitaxel and tanespimycin via micellar nanocarriers: pharmacokinetics, efficacy and metabolomic analysis.胶束纳米载体联合递送紫杉醇和坦西莫司：药代动力学、疗效和代谢组学分析。
PLoS One. 2013;8(3):e58619. doi: 10.1371/journal.pone.0058619. Epub 2013 Mar 7.
9
A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells.曲妥珠单抗和17-AAG联合使用可诱导erbB2过表达的乳腺癌细胞中泛素化增强以及溶酶体途径依赖性erbB2降解和细胞毒性。
Cancer Biol Ther. 2008 Oct;7(10):1630-40. doi: 10.4161/cbt.7.10.6585. Epub 2008 Oct 9.
10
PEG-derivatized octacosanol as micellar carrier for paclitaxel delivery.聚乙二醇衍生化二十八烷醇作为紫杉醇递送的胶束载体。
Int J Pharm. 2016 Mar 16;500(1-2):345-59. doi: 10.1016/j.ijpharm.2016.01.030. Epub 2016 Jan 18.
引用本文的文献
1
A novel ultrasound-responsive cluster bomb system for efficient siRNA delivery in brain.一种用于在大脑中高效递送小干扰RNA的新型超声响应型集束炸弹系统。
Ultrason Sonochem. 2025 Jun 25;120:107446. doi: 10.1016/j.ultsonch.2025.107446.
2
Nanoscale platform for delivery of active IRINOX to combat pancreatic cancer.用于递送活性 IRINOX 以治疗胰腺癌的纳米级平台。
J Control Release. 2021 Feb 10;330:1229-1243. doi: 10.1016/j.jconrel.2020.11.029. Epub 2020 Nov 18.
3
Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer.工程化外泌体实现 miR-21 抑制剂和化疗药物的靶向共递送，逆转结肠癌的耐药性。
J Nanobiotechnology. 2020 Jan 9;18(1):10. doi: 10.1186/s12951-019-0563-2.
4
Docetaxel-trastuzumab stealth immunoliposome: development and in vitro proof of concept studies in breast cancer.多西紫杉醇-曲妥珠单抗隐形免疫脂质体：乳腺癌的研制和体外概念验证研究。
Int J Nanomedicine. 2018 Jun 18;13:3451-3465. doi: 10.2147/IJN.S162454. eCollection 2018.
本文引用的文献
1
Nanomedicines Eradicating Cancer Stem-like Cells in Vivo by pH-Triggered Intracellular Cooperative Action of Loaded Drugs.纳米药物通过负载药物的 pH 触发细胞内协同作用在体内根除癌症干细胞样细胞。
ACS Nano. 2016 Jun 28;10(6):5643-55. doi: 10.1021/acsnano.6b00900. Epub 2016 Apr 25.
2
Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition.通过抑制HSP90显著增强溶酶体靶向性及ErbB2靶向药物递送的效果。
Oncotarget. 2016 Mar 1;7(9):10522-35. doi: 10.18632/oncotarget.7231.
3
Comparison of methods for the fabrication and the characterization of polymer self-assemblies: what are the important parameters?聚合物自组装体的制备与表征方法比较：重要参数有哪些？
Soft Matter. 2016 Feb 21;12(7):2166-76. doi: 10.1039/c5sm01863c. Epub 2016 Jan 12.
4
Targeted delivery of platinum-taxane combination therapy in ovarian cancer.铂类-紫杉烷联合疗法在卵巢癌中的靶向递送
J Control Release. 2015 Dec 28;220(Pt B):651-9. doi: 10.1016/j.jconrel.2015.09.007. Epub 2015 Sep 14.
5
Polypeptide-based nanogels co-encapsulating a synergistic combination of doxorubicin with 17-AAG show potent anti-tumor activity in ErbB2-driven breast cancer models.共封装阿霉素与17-AAG协同组合的基于多肽的纳米凝胶在ErbB2驱动的乳腺癌模型中显示出强大的抗肿瘤活性。
J Control Release. 2015 Jun 28;208:59-66. doi: 10.1016/j.jconrel.2015.02.001. Epub 2015 Feb 3.
6
Targeting HER2 for the treatment of breast cancer.针对乳腺癌的 HER2 靶向治疗。
Annu Rev Med. 2015;66:111-28. doi: 10.1146/annurev-med-042513-015127.
7
Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer.辅助性紫杉醇和曲妥珠单抗用于HER2阳性、淋巴结阴性乳腺癌的治疗
N Engl J Med. 2015 Jan 8;372(2):134-41. doi: 10.1056/NEJMoa1406281.
8
Chirality-mediated polypeptide micelles for regulated drug delivery.手性介导向多肽胶束用于药物可控释放。
Acta Biomater. 2015 Jan;11:346-55. doi: 10.1016/j.actbio.2014.09.043. Epub 2014 Sep 30.
9
Peripherally cross-linking the shell of core-shell polymer micelles decreases premature release of physically loaded combretastatin A4 in whole blood and increases its mean residence time and subsequent potency against primary murine breast tumors after IV administration.对核壳聚合物胶束的外壳进行外周交联，可减少阿霉素A4在全血中的过早释放，并增加其平均驻留时间，进而提高静脉给药后对原发性小鼠乳腺肿瘤的效力。
Pharm Res. 2015 Mar;32(3):1028-44. doi: 10.1007/s11095-014-1515-z. Epub 2014 Sep 16.
10
Bundled assembly of helical nanostructures in polymeric micelles loaded with platinum drugs enhancing therapeutic efficiency against pancreatic tumor.聚合物胶束载铂药物中螺旋纳米结构的捆绑组装增强了对胰腺肿瘤的治疗效果。
ACS Nano. 2014 Jul 22;8(7):6724-38. doi: 10.1021/nn500498t. Epub 2014 Jun 13.
Zotero 插件