1 Department of Radiology, Medical University of Gdansk, Sklodowskiej-Curie 3a, 80-210, Gdansk, Poland.
2 Institute of Statistics, Department of Economic Sciences, Faculty of Management and Economics, Gdansk University of Technology, Gdansk, Poland.
AJR Am J Roentgenol. 2017 Dec;209(6):1348-1352. doi: 10.2214/AJR.17.18079. Epub 2017 Sep 5.
The purpose of this article is to evaluate the utility of ultrasound in identifying carotid bodies (CBs) in patients with drug-resistant arterial hypertension.
We enrolled 13 patients with drug-resistant hypertension into a trial for surgical CB excision. CT angiography (CTA) and Doppler ultrasound (DUS) of the cervical arteries were performed before surgery. CBs were identified in a blind manner at both CTA and DUS. CBs were defined at CTA as ovoid avidly enhancing structures at the inferomedial aspect of the carotid bifurcation. At DUS, CBs were defined as ovoid solid structures in the inferomedial aspect of the bifurcation.
CBs were identified in 12 of 13 patients (23/26 sides) using CTA and in 11 of 13 patients (18/26 sides) using DUS. Identification of CB with DUS and CTA correlated in 17 of 18 cases; in one instance, CB was identified with DUS but not CTA. There was no statistically significant difference in size and volume of CB measured by both methods.
Noncarcinogenic CBs can be visualized using DUS, with good correlation of size and location compared with CTA. The findings show that DUS can be reliably used to further examine the role of CBs in cardiovascular disorders and can be used in conjunction with therapies that target CBs.
本文旨在评估超声在识别耐药性动脉性高血压患者颈动脉体（CB）中的作用。
我们招募了 13 名耐药性高血压患者进行手术 CB 切除术试验。手术前进行 CT 血管造影（CTA）和颈动脉硬化多普勒超声（DUS）检查。在 CTA 和 DUS 上以盲法识别 CB。CTA 上的 CB 定义为颈动脉分叉处下内侧卵圆形强烈增强结构。在 DUS 上，CB 定义为分叉处下内侧卵圆形实性结构。
使用 CTA 在 13 名患者中的 12 名（23/26 侧）和使用 DUS 在 13 名患者中的 11 名（18/26 侧）中识别出 CB。DUS 和 CTA 识别 CB 的相关性在 17/18 例中一致；在一个病例中，DUS 识别出了 CB，但 CTA 没有。两种方法测量的 CB 大小和体积无统计学差异。
使用 DUS 可以可视化非致癌性 CB，其大小和位置与 CTA 相关性良好。这些发现表明 DUS 可以可靠地用于进一步研究 CB 在心血管疾病中的作用，并可与针对 CB 的治疗方法联合使用。
