a Department of cardiology , Adiyaman Education and Research Hospital , Adiyaman , Turkey.
Clin Exp Hypertens. 2018;40(3):251-256. doi: 10.1080/10641963.2017.1356846. Epub 2017 Sep 5.
The presence of premature ventricular contractions (PVCs) is a sign of arrhythmia and typically trigerred by over stimulation of the sympathetic nervous system. This study examined the relationships among PVCs, heart rate variability (HRV), and 24-hour ambulatory blood pressure (ABP) results.
This observational clinical study evaluated a cohort of 100 consecutive patients (58 women and 42 men) with PVCs. The individuals were split into occasional (n = 50) and frequent (n = 50) PVCs groups. All Holter recordings were performed during a working day.
Daytime low-frequency power (LFP), daytime low frequency/high frequency (LF/HF), nighttime LFP, and nighttime LF/HF and 24-hour systolic blood pressure (SBP) were slightly higher in the frequent PVCs group (p = 0.046, p = 0.027, p = 0.038, p = 0.032, and p < 0.001, respectively). Hypertension, LF, LF/HF, 24-hour SBP were positively correlated with PVCs (r = 0.305, p = 0.002; r = 0.269, p = 0.007; r = 0.403, p < 0.001, respectively).
Frequent PVCs reflect dominance of the sympathetic system according to the results of Holter recordings. This study showed that PVC had a significant association with high blood pressure values. Assessment of ABP and HRV in patients with PVCs is part of a comprehensive approach to the assessment of cardiovascular regulation.
室性早搏（PVCs）的存在是心律失常的标志，通常是由交感神经系统过度刺激引发的。本研究检查了 PVCs、心率变异性（HRV）和 24 小时动态血压（ABP）结果之间的关系。
本观察性临床研究评估了 100 例连续 PVCs 患者（58 名女性和 42 名男性）的队列。个体分为偶发性（n=50）和频发（n=50）PVCs 组。所有动态心电图记录均在工作日进行。
频发 PVCs 组白天低频功率（LFP）、白天低频/高频（LF/HF）、夜间 LFP 和夜间 LF/HF 以及 24 小时收缩压（SBP）略高（p=0.046，p=0.027，p=0.038，p=0.032，p<0.001）。高血压、LF、LF/HF、24 小时 SBP 与 PVCs 呈正相关（r=0.305，p=0.002；r=0.269，p=0.007；r=0.403，p<0.001）。
根据动态心电图记录结果，频发 PVCs 反映了交感神经系统的主导地位。本研究表明，PVCs 与高血压值有显著关联。在 PVCs 患者中评估 ABP 和 HRV 是评估心血管调节的综合方法的一部分。
