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慢性拉伸肌肉中神经肌肉传递的强直后增强变化。

Changes in post-tetanic potentiation of neuromuscular transmission in chronically stretched muscle.

作者信息

Yamashita T, Oota I

出版信息

Comp Biochem Physiol A Comp Physiol. 1987;87(3):791-6. doi: 10.1016/0300-9629(87)90402-6.

DOI:10.1016/0300-9629(87)90402-6
PMID:2887363
Abstract
  1. Changes in the parameters of the magnitude of PTP of m.e.p.p. frequency were examined in rat soleus muscles chronically stretched for a variety of durations (4-28 days) by leg-lengthening operations. 2. On day 4 after the operation, the magnitude of PTP in the stretched muscles obviously increased compared to the control muscles. This indicates that Ca2+-conductance in the nerve terminals increases in the stretched muscles at day 4. 3. On day 7 after the operation, there was no significant difference between the magnitudes of PTP in the control and stretched muscles. 4. After day 14 following the operation, the magnitude of PTP in the stretched muscles was smaller than that in the control muscles. This indicates that Ca2+-conductance in the nerve terminals decreases in the stretched muscles after day 14.
摘要
  1. 通过腿部延长手术,对慢性拉伸不同时长(4 - 28天)的大鼠比目鱼肌微小终板电位(m.e.p.p.)频率的强直后增强(PTP)幅度参数变化进行了检测。2. 术后第4天,与对照肌肉相比,拉伸肌肉中的PTP幅度明显增加。这表明术后第4天拉伸肌肉中神经末梢的Ca2+电导增加。3. 术后第7天,对照肌肉和拉伸肌肉的PTP幅度之间没有显著差异。4. 术后第14天之后,拉伸肌肉中的PTP幅度小于对照肌肉。这表明术后14天之后拉伸肌肉中神经末梢的Ca2+电导降低。

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