Carlson Dustin A
Division of Gastroenterology and Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Am J Gastroenterol. 2017 Sep;112(9):1474-1476. doi: 10.1038/ajg.2017.237.
The functional lumen imaging probe (FLIP) provides objective measurement of esophageal distensibility, thus offering a unique and potentially valuable assessment in eosinophilic esophagitis (EoE). Menard-Katcher and colleagues report the first study evaluating use of FLIP in pediatric patients that demonstrated a reduction in esophageal distensibility in patients with EoE compared to patients without EoE. An increase in esophageal distensibility was observed with age among pediatric patients without EoE, but not among those with EoE. While this study further supports the promise of esophageal distensibility assessment in EoE, future work remains needed to optimize FLIP utilization in both research and clinical settings.
功能性管腔成像探头（FLIP）可对食管扩张性进行客观测量，从而为嗜酸性粒细胞性食管炎（EoE）提供独特且可能有价值的评估。梅纳德 - 卡彻及其同事报告了第一项评估FLIP在儿科患者中应用的研究，该研究表明，与非EoE患者相比，EoE患者的食管扩张性降低。在无EoE的儿科患者中，食管扩张性随年龄增加，而在EoE患者中则不然。虽然这项研究进一步支持了食管扩张性评估在EoE中的前景，但仍需要未来的工作来优化FLIP在研究和临床环境中的应用。
