Oakey Zackery, Thai Kevin, Garg Sumit
Gavin Herbert Eye Institute, University of California, Irvine, USA.
Touro University California, Vallejo, USA.
GMS Ophthalmol Cases. 2017 Aug 15;7:Doc21. doi: 10.3205/oc000072. eCollection 2017.
The cornea may become infected and perforated after epithelium-on collagen crosslinking. A healthy 33-year-old male who underwent corneal collagen crosslinking in both eyes developed a purulent keratitis and bilateral corneal perforations, requiring bilateral penetrating keratoplasties. He was exposed to methicillin resistant staphylococcus aureus (MRSA) by a family member with a tracheostomy and was treated with MRSA-directed antibiotics. After prolonged recovery and treatment of his infection, he had acceptable but limited uncorrected visual acuity, with excellent corrected visual acuity. While epithelium-on crosslinking is commonly thought to be associated with a lower risk of postoperative infection, this case illustrates that even epithelium-on treatment may present the patient with a risk of infection. Patients in higher risk groups who are exposed to infectious disease may be more predisposed.
上皮在位胶原交联术后角膜可能发生感染并穿孔。一名健康的33岁男性双眼接受了角膜胶原交联术，发生了化脓性角膜炎和双侧角膜穿孔，需要进行双侧穿透性角膜移植术。他被一名行气管造口术的家庭成员传染了耐甲氧西林金黄色葡萄球菌（MRSA），并接受了针对MRSA的抗生素治疗。经过长时间的感染恢复和治疗后，他的裸眼视力可接受但有限，矫正视力良好。虽然上皮在位交联术通常被认为术后感染风险较低，但该病例表明，即使是上皮在位治疗也可能给患者带来感染风险。暴露于传染病的高风险组患者可能更易患病。
