Boehm Ingrid, Nairz Knud, Morelli John, Silva Hasembank Keller Patricia, Heverhagen Johannes Thomas
1 Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University of Bern, Bern, Switzerland.
2 Radiology Laboratory, Department of BioMedical Research, University of Bern, Bern, Switzerland.
Br J Radiol. 2017 Nov;90(1079):20160647. doi: 10.1259/bjr.20160647. Epub 2017 Sep 6.
Contrast-enhanced radiological examinations are important diagnostic tools in modern medicine. Currently, all approved and available iodinated and gadolinium-based contrast agents are safe and well-tolerated by most patients. However, approximately 2% of patients receiving iodinated contrast media exhibit hypersensitivity reactions. Patients with a history of such a reaction are at increased risk upon reexposure. Therefore, they are subjected to a prophylaxis such as injection of antiallergy drugs or general anaesthesia. The latter procedure is expensive, can burden the patients organism, and besides lacks objective verification. Therefore, the purpose of our review paper is to present and discuss the background and the previous practice, as well as to provide a proposal for a safe individual patient management.
增强放射学检查是现代医学中的重要诊断工具。目前，所有获批且可用的碘造影剂和钆基造影剂对大多数患者而言都是安全且耐受性良好的。然而，约2%接受碘造影剂的患者会出现过敏反应。有此类反应病史的患者再次接触时风险会增加。因此，他们需接受预防措施，如注射抗过敏药物或全身麻醉。后一种方法费用高昂，会给患者机体带来负担，而且缺乏客观验证。因此，我们这篇综述文章的目的是介绍和讨论相关背景及以往做法，并为安全的个体化患者管理提供建议。
