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男性乳腺癌的临床诊断与治疗:24例分析

Clinical Diagnosis and Treatment of Male Breast Cancer:Analysis of 24 Cases.

作者信息

Zhang Yu-Qian, Zhao Hai-Yan, Sun Qiang, Mao Feng, Zhou Yi-Dong, Zhou Jing-Min

机构信息

Department of Breast Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.

出版信息

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017 Aug 20;39(4):568-572. doi: 10.3881/j.issn.1000-503X.2017.04.017.

Abstract

Objective To summarize our experiences in the clinical diagnosis and treatment of male breast cancer(MBC).Methods The clinical date of 24 MBC patients treated in our hospital from January 2006 to December 2012 were retrospective analyzed.Results The average age of these 24 patients was(55.7±2.1) years.All the patients received surgical treatment,and the surgical procedures were simple excision of breast lesion in 6 patients,breast resection alone in 5 patients,and modified radical mastectomy in 13 patients(bilateral in 1 case).The pathological diagnoses included invasive ductal carcinoma in 18 cases,papillary carcinoma in 4 cases,mucinous adenocarcinoma in 1 case,and malignant solitary fibrous tumor in 1 case.Twenty patients received chemotherapy,7 received radiotherapy,and 15 received endocrine therapy after operation.The 5-year survival rate was 54.2%.Conclusions The incidence of MBC is low.This malignancy is mainly seen in elderly individuals,with relatively long disease course,poor prognosis,and high risk of metastasis.MBC is mainly treated by surgery,and adjuvant chemotherapy,radiotherapy,and endocrine therapy may be applied,if appropriate,after the operation.

摘要

目的 总结男性乳腺癌(MBC)的临床诊断与治疗经验。方法 回顾性分析2006年1月至2012年12月在我院接受治疗的24例MBC患者的临床资料。结果 这24例患者的平均年龄为(55.7±2.1)岁。所有患者均接受了手术治疗,手术方式为单纯乳房肿物切除术6例,单纯乳房切除术5例,改良根治性乳房切除术13例(其中1例为双侧)。病理诊断包括浸润性导管癌18例,乳头状癌4例,黏液腺癌1例,恶性孤立性纤维瘤1例。20例患者术后接受了化疗,7例接受了放疗,15例接受了内分泌治疗。5年生存率为54.2%。结论 MBC发病率低。这种恶性肿瘤主要见于老年人,病程相对较长,预后较差,转移风险高。MBC主要通过手术治疗,术后可根据情况适当应用辅助化疗、放疗和内分泌治疗。

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