颞动脉活检在巨细胞动脉炎诊断中的应用：大并不总是好。
Temporal artery biopsy in the diagnosis of giant cell arteritis: Bigger is not always better.
机构信息
Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, Helios Clinic, University Hospital Witten-Herdecke, Wuppertal, Germany.
Homerton University Hospital NHS Foundation Trust, Homerton Row, London, UK.
出版信息
Am J Surg. 2018 Apr;215(4):647-650. doi: 10.1016/j.amjsurg.2017.08.020. Epub 2017 Sep 1.
OBJECTIVE
Accurate early giant cell arteritis (GCA) diagnosis can be established through temporal artery biopsy (TAB). We herein investigate the relationship between specimen length and positive TAB result in a tertiary-care hospital in Germany during a 8-year period. Secondarily, we studied the relationships of specific epidemiological and laboratory parameters with positive TABs.
METHOD
We retrospectively reviewed the medical records of all patients with suspected GCA, who underwent TAB in our institution.
RESULTS
The total sample consisted of 116 patients with a mean age of 76.1 (SD 7.7) years. Mean specimen length post-fixation was 0.94 cm (SD 0.49). The TAB(+) group consisted of 64 patients (55.2%). The specimen length was comparable in the two groups (0.96 cm vs 0.91 cm, p = 0.581). Twenty six TAB(+) patients (41%) had a post-fixation specimen longer than 1 cm, comparable with the respective percentage in the TAB(-) group (42%, p = 1). All laboratory tests performed were statistically significantly different in the two groups.
CONCLUSION
We conclude that TAB length is not associated with the TAB diagnostic yield in patients with clinical suspicion of GCA.
目的
通过颞动脉活检（TAB）可以准确诊断早期巨细胞动脉炎（GCA）。在此，我们研究了德国一家三级保健医院在 8 年期间标本长度与 TAB 阳性结果之间的关系。其次，我们研究了特定的流行病学和实验室参数与 TAB 阳性之间的关系。
方法
我们回顾性地审查了在我们机构接受 TAB 的所有疑似 GCA 患者的病历。
结果
总样本包括 116 名平均年龄为 76.1（SD 7.7）岁的患者。固定后标本的平均长度为 0.94cm（SD 0.49）。TAB（+）组有 64 名患者（55.2%）。两组的标本长度相似（0.96cm 与 0.91cm，p=0.581）。26 名 TAB（+）患者（41%）的固定后标本长度大于 1cm，与 TAB（-）组的相应百分比（42%，p=1）相当。两组之间进行的所有实验室检查均有统计学显著差异。
结论
我们的结论是，在临床怀疑患有 GCA 的患者中，TAB 长度与 TAB 诊断率无关。
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