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肝移植时代过渡阶段先天性胆道闭锁再次Kasai肝门肠吻合术的综述

Review of redo-Kasai portoenterostomy for biliary atresia in the transition to the liver transplantation era.

作者信息

Sumida Wataru, Uchida Hiroo, Tanaka Yujiro, Tainaka Takahisa, Shirota Chiyoe, Murase Naruhiko, Oshima Kazuo, Shirotsuki Ryo, Chiba Kousuke

机构信息

Nagoya University Graduate School of Medicine, Department of Pediatric Surgery.

出版信息

Nagoya J Med Sci. 2017 Aug;79(3):415-420. doi: 10.18999/nagjms.79.3.415.

Abstract

Portoenterostomy (PE) is the standard therapy for biliary atresia (BA). PE offers the chance of survival to children with BA. PE was the ultimate therapeutic modality for BA before liver transplantation (LT) was available. Failure of biliary drainage with PE was almost invariably fatal in children with BA. In such cases, redo-PE was performed to salvage patients following PE failure. PE remains the standard first treatment for BA despite the availability of LT. Further, redo-PE is also performed in a limited number of cases despite the development of LT as an alternative means of PE. However, there is concern that redo-PE increases morbidity at the time of subsequent LT. Laparoscopic redo-PE has recently been described. Laparoscopic redo-PE is expected to reduce complications of LT by preventing abdominal adhesion associated with repetitive surgery. In the present article, the future utility of redo-PE and the history of its changing roles are reviewed.

摘要

肝门空肠吻合术(PE)是胆道闭锁(BA)的标准治疗方法。PE为BA患儿提供了生存机会。在肝移植(LT)出现之前,PE是BA的最终治疗方式。对于BA患儿,PE胆道引流失败几乎总是致命的。在这种情况下,会在PE失败后进行再次PE以挽救患者。尽管有LT,但PE仍然是BA的标准首选治疗方法。此外,尽管LT已发展成为PE的替代方法,但仍有少数病例进行再次PE。然而,有人担心再次PE会增加后续LT时的发病率。最近有人描述了腹腔镜再次PE。腹腔镜再次PE有望通过防止与重复手术相关的腹腔粘连来减少LT的并发症。在本文中,我们回顾了再次PE的未来应用及其角色变化的历史。

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本文引用的文献

2
Long-term outcomes after revision of Kasai portoenterostomy for biliary atresia.胆道闭锁Kasai肝门空肠吻合术翻修后的长期预后
J Hepatobiliary Pancreat Sci. 2016 Nov;23(11):715-720. doi: 10.1002/jhbp.395. Epub 2016 Sep 29.
5
Redo surgery for biliary atresia.胆道闭锁再次手术
Pediatr Surg Int. 2013 Oct;29(10):989-93. doi: 10.1007/s00383-013-3396-3.

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