Commentary: Torpor: The Rise and Fall of 3-Monoiodothyronamine from Brain to Gut-From Gut to Brain?
作者信息
Laurino Annunziatina, Raimondi Laura
机构信息
Department of Psychology, Neurology, Drug Sciences, Health of the Child, Pharmacology, Section of Pharmacology and Toxicology, University of Florence, Florence, Italy.
出版信息
Front Endocrinol (Lausanne). 2017 Aug 22;8:206. doi: 10.3389/fendo.2017.00206. eCollection 2017.
Abstract
摘要
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本文引用的文献
1
In the brain of mice, 3-iodothyronamine (T1AM) is converted into 3-iodothyroacetic acid (TA1) and it is included within the signaling network connecting thyroid hormone metabolites with histamine.在小鼠大脑中，3-碘甲状腺原氨酸（T1AM）会转化为3-碘甲状腺乙酸（TA1），并且它包含在将甲状腺激素代谢物与组胺连接起来的信号网络中。
Eur J Pharmacol. 2015 Aug 15;761:130-4. doi: 10.1016/j.ejphar.2015.04.038. Epub 2015 May 1.
2
3-iodothyroacetic acid, a metabolite of thyroid hormone, induces itch and reduces threshold to noxious and to painful heat stimuli in mice.3-碘甲状腺乙酸是甲状腺激素的一种代谢产物，可诱发小鼠瘙痒并降低其对有害热刺激和疼痛热刺激的阈值。
Br J Pharmacol. 2015 Apr;172(7):1859-68. doi: 10.1111/bph.13032. Epub 2015 Jan 23.
3
Histamine mediates behavioural and metabolic effects of 3-iodothyroacetic acid, an endogenous end product of thyroid hormone metabolism.组胺介导甲状腺激素代谢的内源性终产物3-碘甲状腺乙酸的行为和代谢效应。
Br J Pharmacol. 2014 Jul;171(14):3476-84. doi: 10.1111/bph.12697.
4
Pharmacological effects of 3-iodothyronamine (T1AM) in mice include facilitation of memory acquisition and retention and reduction of pain threshold.3-碘代甲状腺素胺（T1AM）在小鼠中的药理作用包括促进记忆的获得和保持，以及降低痛阈。
Br J Pharmacol. 2013 Jan;168(2):354-62. doi: 10.1111/j.1476-5381.2012.02137.x.
5
3-Iodothyronamine: a modulator of the hypothalamus-pancreas-thyroid axes in mice.3-碘甲状腺原氨酸：调节小鼠下丘脑-胰腺-甲状腺轴的调节剂。
Br J Pharmacol. 2012 May;166(2):650-8. doi: 10.1111/j.1476-5381.2011.01823.x.
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