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[临床环境中成人自闭症谱系障碍患者的睡眠-觉醒模式:一项初步研究]

[Sleep-wake patterns in adults with autism spectrum disorders in a clinical setting: a pilot study].

作者信息

Rosbergen G J, Jansen M P, Rosbergen-De Vries A R, Roke Y, Otten R

出版信息

Tijdschr Psychiatr. 2017;59(9):520-527.

Abstract

The negative consequences of sleep-wake disorders in the general population and in children with an autism spectrum disorder (ASD) are well-established. However, little is known about sleep-wake disorders in adults with ASD.
AIM: To study and measure sleep-wake disorders and sleep-wake patterns in adults in a clinical facility who have been diagnosed primarily as having ASD without any comorbid intellectual disability.
METHOD: We assessed the sleep patterns of 19 patients in a residential facility. We asked patients to provide their sleep history, answer questionnaires and keep a sleep diary (subjective measurement). We also asked patients to collect actigraphy data (objective measurement) for seven days and to provide information about comorbid symptoms of anxiety and depression and use of medication.
RESULTS: Nine patients (47%) had undiagnosed comorbid sleep-wake disorders. Patients in our study overrated their sleep efficiency (diary) compared to objective data (actigraphy). However, patients' subjective sleep quality did match patients' sleep efficiency. Only two out of 14 patients with symptoms of anxiety and/or depression were diagnosed with a comorbid depressive disorder, 15 patients were treated with medication.
CONCLUSION: Sleep-wake disorders and comorbid symptoms of anxiety and depression might be more prevalent in adults with ASD in a residential facility than reported so far. This possibility needs to be considered more carefully during the diagnostic process and during treatment.

摘要

睡眠-觉醒障碍在普通人群以及患有自闭症谱系障碍(ASD)的儿童中的负面后果已得到充分证实。然而,对于患有ASD的成年人的睡眠-觉醒障碍却知之甚少。

目的

研究并测量在临床机构中被主要诊断为患有ASD且无任何合并智力残疾的成年人的睡眠-觉醒障碍及睡眠-觉醒模式。

方法

我们评估了一家寄宿机构中19名患者的睡眠模式。我们要求患者提供睡眠史、回答问卷并记录睡眠日记(主观测量)。我们还要求患者收集七天的活动记录仪数据(客观测量),并提供有关焦虑和抑郁的合并症状以及药物使用情况的信息。

结果

9名患者(47%)患有未被诊断出的合并睡眠-觉醒障碍。与客观数据(活动记录仪)相比,我们研究中的患者高估了他们的睡眠效率(日记)。然而,患者的主观睡眠质量与睡眠效率相符。在14名有焦虑和/或抑郁症状的患者中,只有两名被诊断出合并抑郁症,15名患者接受了药物治疗。

结论

在寄宿机构中,患有ASD的成年人的睡眠-觉醒障碍以及焦虑和抑郁的合并症状可能比迄今报道的更为普遍。在诊断过程和治疗过程中需要更仔细地考虑这种可能性。

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