Yang Quanhe, Tong Xin, Schieb Linda, Vaughan Adam, Gillespie Cathleen, Wiltz Jennifer L, King Sallyann Coleman, Odom Erika, Merritt Robert, Hong Yuling, George Mary G
Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, CDC.
MMWR Morb Mortal Wkly Rep. 2017 Sep 8;66(35):933-939. doi: 10.15585/mmwr.mm6635e1.
The prominent decline in U.S. stroke death rates observed for more than 4 decades has slowed in recent years. CDC examined trends and patterns in recent stroke death rates among U.S. adults aged ≥35 years by age, sex, race/ethnicity, state, and census region.
Trends in the rates of stroke as the underlying cause of death during 2000-2015 were analyzed using data from the National Vital Statistics System. Joinpoint software was used to identify trends in stroke death rates, and the excess number of stroke deaths resulting from unfavorable changes in trends was estimated.
Among adults aged ≥35 years, age-standardized stroke death rates declined 38%, from 118.4 per 100,000 persons in 2000 to 73.3 per 100,000 persons in 2015. The annual percent change (APC) in stroke death rates changed from 2000 to 2015, from a 3.4% decrease per year during 2000-2003, to a 6.6% decrease per year during 2003-2006, a 3.1% decrease per year during 2006-2013, and a 2.5% (nonsignificant) increase per year during 2013-2015. The last trend segment indicated a reversal from a decrease to a statistically significant increase among Hispanics (APC = 5.8%) and among persons in the South Census Region (APC = 4.2%). Declines in stroke death rates failed to continue in 38 states, and during 2013-2015, an estimated 32,593 excess stroke deaths might not have occurred if the previous rate of decline could have been sustained.
Prior declines in stroke death rates have not continued in recent years, and substantial variations exist in timing and magnitude of change by demographic and geographic characteristics. These findings suggest the importance of strategically identifying opportunities for prevention and intervening in vulnerable populations, especially because effective and underused interventions to prevent stroke incidence and death are known to exist.
美国中风死亡率在40多年间显著下降,但近年来这种下降趋势有所放缓。美国疾病控制与预防中心(CDC)按年龄、性别、种族/民族、州及人口普查区域,研究了近年来美国35岁及以上成年人中风死亡率的趋势和模式。
利用国家生命统计系统的数据,分析了2000 - 2015年期间中风作为潜在死因的死亡率趋势。使用Joinpoint软件确定中风死亡率趋势,并估算趋势不利变化导致的中风死亡超额数。
在35岁及以上成年人中,年龄标准化中风死亡率下降了38%,从2000年的每10万人118.4例降至2015年的每10万人73.3例。2000年至2015年中风死亡率的年度百分比变化(APC)有所不同,2000 - 2003年期间每年下降3.4%,2003 - 2006年期间每年下降6.6%,2006 - 2013年期间每年下降3.1%,2013 - 2015年期间每年上升2.5%(无统计学意义)。最后一个趋势段表明,西班牙裔(APC = 5.8%)和南部人口普查区域的人群(APC = 4.2%)的中风死亡率从下降转为具有统计学意义的上升。38个州的中风死亡率下降未能持续,在2013 - 2015年期间,如果之前的下降速度能够持续,估计可能会减少32,593例中风死亡。
近年来中风死亡率先前的下降趋势未能持续,且在人口统计学和地理特征方面,变化的时间和幅度存在显著差异。这些发现表明,战略性地识别预防机会并对弱势群体进行干预非常重要,特别是因为已知存在有效但未充分利用的预防中风发病率和死亡率的干预措施。