Moore J A
Teratog Carcinog Mutagen. 1987;7(3):205-9. doi: 10.1002/tcm.1770070303.
This paper presents an overview of the U.S. Environmental Protection Agency's risk assessment process, describes problems that the Agency faces in conducting risk assessment, in general, and identifies some specific problems that the Agency confronts when conducting risk assessments on suspected developmental toxicants. As noted by the NAS (National Research Council: "Risk Assessment in the Federal Government: Managing the Process." Washington, DC: National Academy Press, 1983, pp 17-83), improving the quality and comprehensiveness of knowledge is the most effective way to improve risk assessment, but some limitations are inherent and may remain unresolvable. Therefore, inferences will always be required. The Agency's challenge is to ensure that these inferences are as soundly based as possible.
本文概述了美国环境保护局的风险评估过程，描述了该机构在进行风险评估时总体上面临的问题，并确定了该机构在对疑似发育毒物进行风险评估时所面临的一些具体问题。正如美国国家研究委员会（NAS：《联邦政府中的风险评估：管理流程》。华盛顿特区：美国国家科学院出版社，1983年，第17 - 83页）所指出的，提高知识的质量和全面性是改进风险评估的最有效方法，但有些局限性是固有的，可能仍然无法解决。因此，总是需要进行推断。该机构面临的挑战是确保这些推断尽可能有充分的依据。
