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透视辅助与无透视内镜超声引导下胰液积聚经壁引流的比较研究

Fluoroscopy-assisted vs fluoroless endoscopic ultrasound-guided transmural drainage of pancreatic fluid collections: A comparative study.

作者信息

Consiglieri Claudia F, Gornals Joan B, Busquets Juli, Peláez Nuria, Secanella Lluis, De-La-Hera Meritxell, Sanzol Resurrección, Fabregat Joan, Castellote José

机构信息

Endoscopy Unit, Department of Digestive Diseases, Hospital Universitari de Bellvitge-IDIBELL, Barcelona, Catalonia, Spain.

Endoscopy Unit, Department of Digestive Diseases, Hospital Universitari de Bellvitge-IDIBELL, Barcelona, Catalonia, Spain; Universitat Oberta de Catalunya, Hospital Universitari de Bellvitge-IDIBELL, Barcelona, Catalonia, Spain.

出版信息

Gastroenterol Hepatol. 2018 Jan;41(1):12-21. doi: 10.1016/j.gastrohep.2017.07.008. Epub 2017 Sep 5.

Abstract

INTRODUCTION

The need for fluoroscopy guidance in patients undergoing endoscopic ultrasound-guided transmural drainage (EUS-TMD) of peripancreatic fluid collections (PFCs) remains unclear.

AIMS

The aim of this study was to compare general outcomes of EUS-TMD of PFCs under fluoroscopy (F) vs fluoroless (FL).

METHODS

This is a comparative study with a retrospective analysis of a prospective and consecutive inclusion database at a tertiary centre, from 2009 to 2015. All patients were symptomatic pseudocyst (PSC) and walled-off pancreatic necrosis (WON). Two groups were assigned depending on availability of fluoroscopy. The groups were heterogeneous in terms of their demographic characteristics, PFCs and procedure. The main outcome measures included technical and clinical success, incidences, adverse events (AEs), and follow-up.

RESULTS

Fifty EUS-TMD of PFCs from 86 EUS-guided drainages were included during the study period. Group F included 26 procedures, PSC 69.2%, WON 30.8%, metal stents 61.5% (46.1% lumen-apposing stent) and plastic stents 38.5%. Group FL included 24 procedures, PSC 37.5%, WON 62.5%, and metal stents 95.8% (lumen-apposing stents). Technical success was 100% in both groups, and clinical success was similar (F 88.5%, FL 87.5%). Technical incidences and intra-procedure AEs were only described in group F (7.6% and 11.5%, respectively) and none in group FL. Procedure time was less in group FL (8min, p=0.0341).

CONCLUSIONS

Fluoroless in the EUS-TMD of PFCs does not involve more technical incidences or intra-procedure AEs. Technical and clinical success was similar in the two groups.

摘要

引言

对于接受内镜超声引导下经壁引流(EUS-TMD)治疗胰腺周围液体积聚(PFCs)的患者,是否需要荧光透视引导仍不明确。

目的

本研究旨在比较荧光透视引导(F)与无荧光透视引导(FL)下EUS-TMD治疗PFCs的总体结果。

方法

这是一项比较研究,对2009年至2015年在一家三级中心前瞻性连续纳入的数据库进行回顾性分析。所有患者均为有症状的假性囊肿(PSC)和包裹性胰腺坏死(WON)。根据荧光透视的可用性将患者分为两组。两组在人口统计学特征、PFCs和操作方面存在异质性。主要结局指标包括技术和临床成功率、发生率、不良事件(AE)及随访情况。

结果

在研究期间,86例EUS引导下引流中有50例为PFCs的EUS-TMD。F组包括26例操作,其中PSC占69.2%,WON占30.8%,金属支架占61.5%(管腔对合支架占46.1%),塑料支架占38.5%。FL组包括24例操作,PSC占37.5%,WON占62.5%,金属支架占95.8%(管腔对合支架)。两组技术成功率均为100%,临床成功率相似(F组88.5%,FL组87.5%)。仅F组描述了技术发生率和术中AE(分别为7.6%和11.5%),FL组无相关情况。FL组操作时间更短(8分钟,p=0.0341)。

结论

PFCs的EUS-TMD中无荧光透视引导并不涉及更多的技术发生率或术中AE。两组技术和临床成功率相似。

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