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含糖类表面活性剂的磷酸钙骨水泥:第一部分——孔隙率、凝固时间和抗压强度

Calcium Phosphate Bone Cements Including Sugar Surfactants: Part One-Porosity, Setting Times and Compressive Strength.

作者信息

Bercier Ariane, Gonçalves Stéphane, Lignon Olivier, Fitremann Juliette

机构信息

Université de Toulouse, Laboratoire des IMRCP, CNRS-Université Paul Sabatier, Bâtiment 2R1, 118 Route de Narbonne, 31062 Toulouse Cedex 9, France.

Teknimed SA, 11 rue Apollo, ZI Montredon, 31240 L'UNION, France.

出版信息

Materials (Basel). 2010 Sep 30;3(10):4695-4709. doi: 10.3390/ma3104695.

Abstract

Addition of sugar surfactants, sucrose fatty acid esters and alkylpolyglucosides, to calcium phosphate cement designed for bone reconstruction is described. Thanks to their surface activity and through their adsorption at the surface of the calcium phosphate particles, they both induced a strong increase in the porosity (quantified by Image Analysis) and brought a very good workability. Other properties typically studied for these cements are reported, including setting times, compressive strength, cohesion in water, and effect of sterilization on these properties. The whole study brought good insight in the interest of adding these mild surfactants to improve several properties of the calcium phosphate cement, without impairing their function.

摘要

描述了将糖表面活性剂、蔗糖脂肪酸酯和烷基多苷添加到用于骨重建的磷酸钙骨水泥中的情况。由于它们的表面活性以及在磷酸钙颗粒表面的吸附作用,它们既使孔隙率大幅增加(通过图像分析量化),又带来了非常好的可加工性。还报告了这些骨水泥通常研究的其他性能,包括凝结时间、抗压强度、在水中的粘结性以及灭菌对这些性能的影响。整个研究很好地洞察了添加这些温和表面活性剂以改善磷酸钙骨水泥的多种性能而又不损害其功能的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad9c/5445786/62b2dec6d6d6/materials-03-04695-g001.jpg

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