Division of Applied Material Science, Department of Engineering Sciences, Uppsala University, Uppsala SE-751 21, Sweden.
Division of Nanotechnology and Functional Materials, Department of Engineering Sciences, Uppsala University, Uppsala SE-751 21, Sweden.
J Dent. 2017 Dec;67:53-57. doi: 10.1016/j.jdent.2017.09.001. Epub 2017 Sep 5.
The combination of TiO and HO under light activation constitutes a promising method for disinfection of dental prosthetics and implants, due to production of reactive oxygen species (ROS). The aim of this work was to investigate the organic degradation ability of TiO particles in combination with HO and under light activation utilizing the organic dye rhodamine B (RhB).
Five different types of TiO particles, consisting of anatase, rutile, or a mixture of these crystalline phases, were combined with HO and RhB, and subsequently exposed to UV (365nm) or visible (405nm) light at an irradiance of 2.1mW/cm.
It was found that rutile in combination with low concentrations of HO (1.0-3.5mM) resulted in a degradation of RhB of 96% and 77% after 10min exposure to 365nm and 405nm light, respectively, which was the highest degradation of all test groups. Control measurements performed without light irradiation or irradiation at 470nm, or without TiO particles resulted in little or no degradation of RhB.
Low HO concentrations (1.0mM-3.5mM) and visible light (405nm) used in combination with rutile TiO particles showed the highest RhB degradation capacity.
A combination of TiO particles and HO exposed to low energy UV or high energy visible light has an organic degradation capability that could be utilized in applications to kill or inactivate bacteria on medical devices such as dental implants for treatment against, e.g., peri-implantitis.
TiO 和 HO 在光激活下的结合构成了一种有前途的牙科修复体和植入物消毒方法，因为它可以产生活性氧物质（ROS）。本研究的目的是利用有机染料罗丹明 B（RhB）研究 TiO 颗粒在与 HO 结合并在光激活下的有机降解能力。
将五种不同类型的 TiO 颗粒（包括锐钛矿、金红石或这些晶相的混合物）与 HO 和 RhB 结合，然后在 365nm 或 405nm 光（辐照度为 2.1mW/cm）下暴露。
发现金红石与低浓度 HO（1.0-3.5mM）结合，在分别用 365nm 和 405nm 光照射 10min 后，RhB 的降解率分别达到 96%和 77%，是所有测试组中最高的。未进行光照或在 470nm 下进行光照或没有 TiO 颗粒的对照测量导致 RhB 的降解很少或没有。
低浓度 HO（1.0mM-3.5mM）和可见光（405nm）与金红石 TiO 颗粒结合使用时，显示出最高的 RhB 降解能力。
TiO 颗粒和 HO 的组合在低能量 UV 或高能量可见光下暴露具有有机降解能力，可用于杀死或灭活医疗设备（如牙科植入物）上的细菌，例如治疗种植体周围炎。
