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双胎妊娠延迟间隔分娩:三例报告及文献综述

Delayed-interval delivery in twin pregnancies: report of three cases and literature review.

作者信息

Benito Vielba Marta, De Bonrostro Torralba Carlos, Pallares Arnal Victoria, Herrero Serrano Rebeca, Tejero Cabrejas Eva Lucía, Campillos Maza Jose Manuel

机构信息

a Departamento de Obstetricia y Ginecología , Hospital Universitario Miguel Servet , Zaragoza , Spain.

出版信息

J Matern Fetal Neonatal Med. 2019 Jan;32(2):351-355. doi: 10.1080/14767058.2017.1378336. Epub 2017 Oct 5.

Abstract

INTRODUCTION

Delayed delivery is sometimes performed in selected multifetal pregnancies when the first twin birth occurs inevitably. The aim of this procedure is to improve the prognosis and decrease the morbidity and mortality of the second twin. We report three cases of delayed-interval delivery of dichorionic-diamniotic twin pregnancies assisted in our center between 2015 and 2017. After the first twin delivery, the second twin was left in utero and the patient received tocolytic therapy and antibiotics. Cervical cerclage was not performed.

RESULTS

Our patients were admitted between 21 + 3 and 23 + 6 weeks of gestation. We achieved an average interval delivery of 6.33 d. Four out of six twins did not survive the delayed interval procedure. The average stay of the first and second twins that were admitted to the neonatal intensive care unit (NICU) was of 72 d (28-116) and 39.5 d (12-67), respectively. The first twin birth was vaginal in all cases, while the second twin delivery was performed by cesarean section in two out of our three patients. Our neonatal results are not favorable, probably due to the extreme prematurity.

CONCLUSIONS

Delayed delivery of the second twin before 28 weeks of gestation can be an alternative for the obstetrician since it could prolong the pregnancy until a gestational age which confers a better prognosis and a better perinatal outcome for the second twin.

摘要

引言

在某些单绒毛膜双胎妊娠中,当第一个胎儿不可避免地早产时,有时会进行延迟分娩。该操作的目的是改善预后并降低第二个胎儿的发病率和死亡率。我们报告了2015年至2017年在我们中心协助下进行的三例双绒毛膜双羊膜囊双胎妊娠延迟间隔分娩的病例。在第一个胎儿分娩后,将第二个胎儿留在子宫内,患者接受了宫缩抑制剂治疗和抗生素治疗。未进行宫颈环扎术。

结果

我们的患者在妊娠21 + 3至23 + 6周之间入院。我们实现了平均间隔6.33天的分娩。六对双胞胎中有四对在延迟间隔过程中未能存活。入住新生儿重症监护病房(NICU)的第一个和第二个双胞胎的平均住院时间分别为72天(28 - 116天)和39.5天(12 - 67天)。所有病例中第一个胎儿均经阴道分娩,而在我们的三名患者中,有两名患者的第二个胎儿通过剖宫产分娩。我们的新生儿结果并不理想,可能是由于极端早产。

结论

对于产科医生来说,在妊娠28周前延迟第二个胎儿的分娩可能是一种选择,因为它可以将妊娠延长至一个能为第二个胎儿带来更好预后和围产期结局的孕周。

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