4th Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, 49 Konstantinoupoleos str, 54642, Thessaloniki, Greece.
Arch Gynecol Obstet. 2012 Sep;286(3):613-7. doi: 10.1007/s00404-012-2362-y. Epub 2012 May 5.
To study the effectiveness of emergency cervical cerclage in order to delay the delivery interval after miscarriage of the first fetus in dichorionic twin pregnancies.
Dichorionic twin pregnancies after miscarriage of the first fetus (<24 weeks) were exclusively included in the present analysis. Prolongation of delivery interval was managed with additional emergency cervical cerclage in the already initiated tocolytic therapy. Obstetric outcomes (cervical dilatation, gestational age at delivery of the first twin, interval between miscarriage and delivery of the second fetus) and neonatal outcomes [neonatal birth weight, Apgar score in the first and fifth minute, admission to Neonatal Intensive Care Unit (NICU)] of the second twin were analyzed.
Five cases of dichorionic twin pregnancies were included in our study. Cervical dilatation (mean ± SD) at admission time was 3.7 ± 1.4 cm. The gestational week at delivery of the first twin was 20.6 ± 2.6. The median delivery interval was 72 days and the maximum 121 days. Mean gestational age at delivery of the second twin was 28.8 ± 7.2 weeks and mean birth weight 1,772.5 ± 742 g. The rate of live birth was 80 %, while NICU admission was demanded in 75 % of the live births. All neonates discharged from NICU remained alive after 1 month of life.
The present study demonstrated beneficial effect concerning obstetric and neonatal outcomes of the second twin after performing emergency cervical cerclage to postpone the delivery interval in premature dichorionic twin pregnancies.
研究紧急宫颈环扎术对延长双绒毛膜性一胎流产后分娩间隔的有效性。
本研究仅纳入一胎流产(<24 周)后的双绒毛膜性妊娠。在已开始的保胎治疗中,通过额外的紧急宫颈环扎术来延长分娩间隔。分析第二胎的产科结局(宫颈扩张程度、第一胎分娩时的孕周、第二胎流产与分娩之间的间隔)和新生儿结局[第二胎新生儿出生体重、第 1 分钟和第 5 分钟的 Apgar 评分、入住新生儿重症监护病房(NICU)]。
本研究纳入了 5 例双绒毛膜性妊娠。入院时的宫颈扩张度(均值±标准差)为 3.7±1.4cm。第一胎的分娩孕周为 20.6±2.6 周。中位分娩间隔为 72 天,最长为 121 天。第二胎的平均分娩孕周为 28.8±7.2 周,平均出生体重为 1772.5±742g。活产率为 80%,而活产儿中 75%需要入住 NICU。所有从 NICU 出院的新生儿在 1 个月的生命后均存活。
本研究表明,在早产双绒毛膜性妊娠中进行紧急宫颈环扎术以延长分娩间隔,对第二胎的产科和新生儿结局有有益的影响。