Ito Akihiro, Ishida Tadashi, Tachibana Hiromasa, Ito Yuhei, Takaiwa Takuya, Fujii Hiroyuki, Hashimoto Toru, Nakajima Hiroshi, Amemura-Maekawa Junko
Department of Respiratory Medicine, Kurashiki Central Hospital.
Department of Respiratory Medicine, National Hospital Organization Minami Kyoto Hospital.
Jpn J Infect Dis. 2017 Nov 22;70(6):660-662. doi: 10.7883/yoken.JJID.2016.548. Epub 2017 Sep 11.
Legionella species are important causative pathogens for severe community-acquired pneumonia (CAP). Most cases of Legionella pneumonia are due to Legionella pneumophila serogroup 1, and CAP due to L. pneumophila serogroup 9 is rare. A fourth case of CAP due to L. pneumophila serogroup 9 has been reported, and initial treatment using single-dose oral azithromycin appeared useful. Azithromycin or fluoroquinolone injection is usually recommended for the treatment of Legionella pneumonia, and no previous reports have shown the effectiveness of single-dose oral azithromycin. This case report is therefore valuable from the perspective of possible treatment for mild to moderate Legionella pneumonia using single-dose oral azithromycin.
嗜肺军团菌是严重社区获得性肺炎（CAP）的重要致病病原体。大多数军团菌肺炎病例是由嗜肺军团菌血清型1引起的，由嗜肺军团菌血清型9引起的CAP很少见。已有第四例由嗜肺军团菌血清型9引起的CAP病例报告，使用单剂量口服阿奇霉素进行初始治疗似乎有效。阿奇霉素或氟喹诺酮类注射剂通常被推荐用于治疗军团菌肺炎，此前尚无报告表明单剂量口服阿奇霉素的有效性。因此，从使用单剂量口服阿奇霉素治疗轻至中度军团菌肺炎的可能性来看，本病例报告具有重要价值。
