关于《奥美沙坦酯活性代谢物奥美沙坦在高血压患者中的群体药代动力学建模》的评论 - Suppr

Suppr

超能文献

Comments on: "Population Pharmacokinetic Modeling of Olmesartan, the Active Metabolite of Olmesartan Medoxomil, in Patients with Hypertension".

作者信息

Srinivas Nuggehally R

机构信息

Zydus Research Centre, Cadila Health Care Ltd, Sakhlej-Bavla NH No 8A, Moraiya, Ahmedabad, Gujarat, 382210, India.

出版信息

Eur J Drug Metab Pharmacokinet. 2017 Dec;42(6):1019-1021. doi: 10.1007/s13318-017-0432-z.

DOI:10.1007/s13318-017-0432-z

PMID:28890991

Abstract

摘要

相似文献

Comments on: "Population Pharmacokinetic Modeling of Olmesartan, the Active Metabolite of Olmesartan Medoxomil, in Patients with Hypertension".关于《奥美沙坦酯活性代谢物奥美沙坦在高血压患者中的群体药代动力学建模》的评论

Eur J Drug Metab Pharmacokinet. 2017 Dec;42(6):1019-1021. doi: 10.1007/s13318-017-0432-z.

Population Pharmacokinetic Modeling of Olmesartan, the Active Metabolite of Olmesartan Medoxomil, in Patients with Hypertension.奥美沙坦酯活性代谢产物奥美沙坦在高血压患者中的群体药代动力学建模

Eur J Drug Metab Pharmacokinet. 2017 Aug;42(4):573-581. doi: 10.1007/s13318-016-0371-0.

A double-blind, dose-response study of the efficacy and safety of olmesartan medoxomil in children and adolescents with hypertension.一项评估奥美沙坦酯治疗儿童和青少年高血压的疗效和安全性的双盲、剂量反应研究。

Hypertension. 2010 Jun;55(6):1323-30. doi: 10.1161/HYPERTENSIONAHA.109.147702. Epub 2010 Apr 12.

Antihypertensive efficacy of olmesartan medoxomil and candesartan cilexetil in achieving 24-hour blood pressure reductions and ambulatory blood pressure goals.奥美沙坦酯和坎地沙坦酯在实现24小时血压降低及动态血压目标方面的降压疗效。

Clin Drug Investig. 2006;26(4):185-93. doi: 10.2165/00044011-200626040-00002.

Pharmacokinetics of olmesartan medoxomil plus hydrochlorothiazide combination in healthy subjects.奥美沙坦酯与氢氯噻嗪复方制剂在健康受试者中的药代动力学

Clin Drug Investig. 2006;26(1):29-34. doi: 10.2165/00044011-200626010-00004.

Olmesartan medoxomil: the seventh angiotensin receptor antagonist.奥美沙坦酯：第七种血管紧张素受体拮抗剂。

Ann Pharmacother. 2003 Jan;37(1):99-105. doi: 10.1345/aph.1C197.

The role of olmesartan medoxomil in the management of hypertension.奥美沙坦酯在高血压管理中的作用。

Drugs. 2004;64(24):2731-9. doi: 10.2165/00003495-200464240-00002.

Efficacy and safety of olmesartan medoxomil and hydrochlorothiazide compared with benazepril and amlodipine besylate.与苯那普利和苯磺酸氨氯地平相比，奥美沙坦酯氢氯噻嗪片的疗效与安全性

Am J Cardiovasc Drugs. 2007;7(5):361-72. doi: 10.2165/00129784-200707050-00006.

Olmesartan medoxomil.奥美沙坦酯

Drugs. 2002;62(9):1345-53; discussion 1354-6. doi: 10.2165/00003495-200262090-00005.

Use of 24-hour ambulatory blood pressure monitoring to assess antihypertensive efficacy: a comparison of olmesartan medoxomil, losartan potassium, valsartan, and irbesartan.使用24小时动态血压监测评估降压疗效：奥美沙坦酯、氯沙坦钾、缬沙坦和厄贝沙坦的比较

Am J Cardiovasc Drugs. 2005;5(1):41-50. doi: 10.2165/00129784-200505010-00006.

本文引用的文献

Eur J Drug Metab Pharmacokinet. 2017 Aug;42(4):573-581. doi: 10.1007/s13318-016-0371-0.

Pharmacokinetic interaction between rosuvastatin and olmesartan: a randomized, open-label, 3-period, multiple-dose crossover study in healthy Korean male subjects.瑞舒伐他汀与奥美沙坦之间的药代动力学相互作用：一项在健康韩国男性受试者中进行的随机、开放标签、3期、多剂量交叉研究。

Clin Ther. 2014 Aug 1;36(8):1159-70. doi: 10.1016/j.clinthera.2014.06.022. Epub 2014 Jul 10.

Development of a population pharmacokinetic model to describe olmesartan medoxomil/ hydrochlorothiazide (20/12.5 mg) FDC tablet in male healthy South Korean subjects.建立群体药代动力学模型以描述奥美沙坦酯/氢氯噻嗪（20/12.5毫克）固定剂量复方片剂在韩国健康男性受试者中的情况。

Int J Clin Pharmacol Ther. 2014 Aug;52(8):676-83. doi: 10.5414/CP202046.

Interindividual variability of carboxymethylenebutenolidase homolog, a novel olmesartan medoxomil hydrolase, in the human liver and intestine.人肝和肠中羧甲烯基丁烯二醛酶同系物（新型奥美沙坦酯水解酶）的个体间变异性。

Drug Metab Dispos. 2013 May;41(5):1156-62. doi: 10.1124/dmd.113.051482. Epub 2013 Mar 7.

Association study of genetic polymorphisms of drug transporters, SLCO1B1, SLCO1B3 and ABCC2, in African-Americans, Hispanics and Caucasians and olmesartan exposure.药物转运体 SLCO1B1、SLCO1B3 和 ABCC2 的遗传多态性与非洲裔美国人、西班牙裔和白种人以及奥美沙坦暴露的关联研究。

J Hum Genet. 2012 Aug;57(8):531-44. doi: 10.1038/jhg.2012.63. Epub 2012 Jun 14.

Paraoxonase 1 as a major bioactivating hydrolase for olmesartan medoxomil in human blood circulation: molecular identification and contribution to plasma metabolism.对氧磷酶 1 作为奥美沙坦酯在人血液循环中的主要生物激活水解酶：分子鉴定及其对血浆代谢的贡献。

Drug Metab Dispos. 2012 Feb;40(2):374-80. doi: 10.1124/dmd.111.041475. Epub 2011 Nov 15.

Comparative pharmacodynamics of olmesartan and azelnidipine in patients with hypertension: a population pharmacokinetic/pharmacodynamic analysis.奥美沙坦和阿折地平在高血压患者中的比较药效学：基于群体药代动力学/药效学分析。

Drug Metab Pharmacokinet. 2009;24(4):376-88. doi: 10.2133/dmpk.24.376.

Prediction of biliary excretion in rats and humans using molecular weight and quantitative structure-pharmacokinetic relationships.利用分子量和定量构效关系预测大鼠和人类的胆汁排泄情况。

AAPS J. 2009 Sep;11(3):511-25. doi: 10.1208/s12248-009-9124-1. Epub 2009 Jul 11.

Evaluation of population pharmacokinetics and exposure-response relationship with coadministration of amlodipine besylate and olmesartan medoxomil.苯磺酸氨氯地平和奥美沙坦酯联合给药的群体药代动力学及暴露-反应关系评估。

J Clin Pharmacol. 2008 Jul;48(7):823-36. doi: 10.1177/0091270008317847. Epub 2008 May 19.

OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker.新型血管紧张素II阻断剂奥美沙坦的肝胆转运涉及有机阴离子转运多肽1B1（OATP1B1）、有机阴离子转运多肽1B3（OATP1B3）和多药耐药相关蛋白2（mrp2）。

Drug Metab Dispos. 2006 May;34(5):862-9. doi: 10.1124/dmd.105.008888. Epub 2006 Feb 24.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验