Department of Dermatology, Shiga University of Medical Science, Otsu, Japan.
J Dermatol. 2018 Jan;45(1):72-75. doi: 10.1111/1346-8138.14039. Epub 2017 Sep 11.
Buruli ulcer is the third most common mycobacterial infection next to tuberculosis and leprosy caused by Mycobacterium ulcerans. Although it affects the skin, subcutaneous tissues, muscles and sometimes bones, there is no reliable evidence to determine the extent of debridement. We present here a case of Buruli ulcer treated successfully with a preoperative mapping biopsy procedure, which had been self-medicated with occlusive dressing. Because Buruli ulcer is accompanied by subtle pain, patients and clinicians tend to initially treat the ulcer with occlusive dressing therapy, which leads to the misdiagnosis of Buruli ulcer as a common bacterial infection only judging from bacterial culture of the surface of the ulcer. We propose the efficacy of mapping biopsy for treating Buruli ulcer.
布鲁里溃疡是仅次于结核和麻风的第三大常见分枝杆菌感染，由溃疡分枝杆菌引起。尽管它会影响皮肤、皮下组织、肌肉，有时还会影响骨骼，但目前尚无可靠证据来确定清创的范围。我们在此介绍一例布鲁里溃疡病例，该病例成功地接受了术前定位活检手术治疗，该手术曾用封闭敷料进行过自我治疗。由于布鲁里溃疡伴有轻微疼痛，患者和临床医生最初倾向于用封闭敷料疗法治疗溃疡，这导致布鲁里溃疡仅根据溃疡表面的细菌培养被误诊为常见细菌感染。我们提出了定位活检治疗布鲁里溃疡的疗效。
