Shen Huijun, Mao Jianhua, Shu Qiang, Du Lizhong
Departments of Nephrology, *Thoracic and Cardiovascular Surgery, and #Neonatology; The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China. Correspondence to: Dr JH Mao, Department of Nephrology, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China.
Indian Pediatr. 2017 Aug 15;54(8):675-677. doi: 10.1007/s13312-017-1132-0.
Henoch-Schönlein purpura (HSP) is the most common vasculitis in childhood. Severe central nervous system (CNS) involvement is rare in HSP.
Three children with features of HSP presented with seizures and CNS dysfunction.
All three children had abnormalities on neuroimaging; 2 had complete remission but one was left with severe neurological damage.
HSP patients may rarely present with CNS involvement with a prolonged course requiring aggressive treatment.
过敏性紫癜（HSP）是儿童期最常见的血管炎。严重的中枢神经系统（CNS）受累在HSP中较为罕见。
三名具有HSP特征的儿童出现癫痫发作和中枢神经系统功能障碍。
所有三名儿童神经影像学检查均有异常；2例完全缓解，但1例遗留严重神经损伤。
HSP患者可能很少出现中枢神经系统受累，病程较长，需要积极治疗。
