Extracellular matrix and its role in conveying glial/neural interactions in health and disease.
作者信息
Fernandes de Lima Vera Maura, Hanke Wolfgang
机构信息
Centro de Biotecnologia, CNEN-IPEN/SP, Av. Lineu Prestes 2242, Campus USP, São Paulo, SP, Brazil, 05508-000.
LIM-26 Faculdade de Medicina da USP-SP, São Paulo, Brazil.
出版信息
J Integr Neurosci. 2017;16(1):93-106. doi: 10.3233/JIN-170012.
PMID:28891503
Abstract
We review the concepts and findings that may be related to the occurrence of non-linear glial/neural dynamics involving interactions between polyelectrolytes of the extracellular matrix and the basement membranes that cover the endfeet of glia at CNS interfaces. Distortions of perception and blocking of learning expressed in functional syndromes are interpreted as macroscopic electrochemical patterns that emerge in grey matter through glial/neural interactions.
摘要
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