Department of Chemistry and Center for Integrated Protein Science CIPSM, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377, München, Germany.
Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14536-14539. doi: 10.1002/anie.201708178. Epub 2017 Oct 12.
Hemithioindigo molecular motors undergo very fast unidirectional rotation upon irradiation with visible light, which has prevented a complete analysis of their working mechanism. In this work, we have considerably slowed down their motion by using a new synthesis for sterically hindered motor derivatives. This method allowed the first observation of all four intermediate states populated during rotation. The exact order in which each isomeric state is formed under irradiation conditions was elucidated using low temperature H NMR spectroscopy in conjunction with other analytical methods. At the same time, complete unidirectionality could also be directly shown. Access to slowly rotating hemithioindigo motors opens up a plethora of new applications for visible-light-induced unidirectional motions, especially in areas such as catalysis, smart materials, and supramolecular chemistry.
手性硫靛分子马达在可见光照射下会发生非常快速的单向旋转，这使得对其工作机制的全面分析变得困难。在这项工作中，我们通过使用新的合成方法制备了位阻较大的马达衍生物，从而显著减缓了马达的运动速度。这种方法使得首次能够观察到在旋转过程中所有四个中间态的填充情况。通过低温 H NMR 光谱与其他分析方法相结合，阐明了在光照条件下每种异构态形成的确切顺序。同时，也可以直接证明完全的单向性。对缓慢旋转的手性硫靛马达的研究为可见光诱导的单向运动开辟了许多新的应用，特别是在催化、智能材料和超分子化学等领域。
