Albers Jessica, Jäkel Anne, Wellmann Kai, von Hehn Ulrike, Schmidt Tobias
Osteopathie Schule Deutschland, Hamburg, Germany.
Complement Med Res. 2018;25(2):122-128. doi: 10.1159/000464343. Epub 2017 Sep 12.
To assess the effectiveness of osteopathic intervention (OI) and general osteopathic treatment (GOT) in individuals with fibromyalgia syndrome (FMS).
The trial was designed as a randomized controlled trial with 2 osteopathic interventions and 1 untreated control group. The patients in the two osteopathic groups received 10 osteopathic treatments (OI or GOT) within a time period of 12 weeks. The control group did not receive any osteopathic treatment. The primary outcome was the average pain intensity (API) assessed by visual analog scale (VAS). Secondary outcomes were the pressure-pain threshold rated by means of a tender point score, and disease severity, assessed by the Fibromyalgia Impact Questionnaire (FIQ).
50 patients were randomized. The primary outcome parameter API decreased from 7.2 to 4.7 in the OI group, from 6.3 to 4.3 in the GOT group, and increased slightly in the control group from 6.2 to 6.6. There were significant differences for the change in API between the OI group and the control group (VAS: 2.9, 95% confidence interval (CI) = 1.12-4.52), and between the GOT group and the control group (VAS: 2.4, 95% CI = 0.65-4.11), but no significant differences between the OI group and the GOT group. There were no significant differences for the secondary outcome parameters between the groups.
A series of osteopathic treatments might be beneficial for patients suffering from FMS.
评估整骨疗法干预（OI）和一般整骨治疗（GOT）对纤维肌痛综合征（FMS）患者的疗效。
该试验设计为随机对照试验，包括两种整骨疗法干预组和1个未治疗的对照组。两个整骨疗法组的患者在12周内接受10次整骨治疗（OI或GOT）。对照组未接受任何整骨治疗。主要结局是通过视觉模拟量表（VAS）评估的平均疼痛强度（API）。次要结局是通过压痛点评分评定的压痛阈值，以及通过纤维肌痛影响问卷（FIQ）评估的疾病严重程度。
50例患者被随机分组。OI组的主要结局参数API从7.2降至4.7，GOT组从6.3降至4.3，而对照组则从6.2略有升至6.6。OI组与对照组之间的API变化存在显著差异（VAS：2.9，95%置信区间（CI）=1.12 - 4.52），GOT组与对照组之间也存在显著差异（VAS：2.4，95%CI = 0.65 - 4.11），但OI组与GOT组之间无显著差异。各组间次要结局参数无显著差异。
一系列整骨疗法可能对FMS患者有益。
