Mohapatra Vandana, Patra Susama, Nayak Mamita, Gharei Radhamohan, Sahoo Nibedita
Senior Resident, Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India.
Additional Professor and Head, Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India.
J Clin Diagn Res. 2017 Jul;11(7):QD05-QD07. doi: 10.7860/JCDR/2017/27199.10247. Epub 2017 Jul 1.
Ovarian fibromas are benign sex cord stromal tumours occurring in peri-menopausal and post-menopausal women. These tumours are composed of spindle fibroblastic cells producing collagen. They are almost always endocrine-inert and are rarely associated with hormone production. We report herein a case of a 60-year-old Indian woman presenting as post-menopausal bleeding. Imaging studies and endometrial biopsy revealed a right ovarian solid tumour coexisting with thickened proliferative endometrium, other causes of hyperoestrogenism being excluded in the woman. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Histopathology showed cellular fibroma of right ovary and proliferative endometrium with foci of hyperplasia without atypia.
卵巢纤维瘤是发生于围绝经期和绝经后女性的良性性索间质肿瘤。这些肿瘤由产生胶原蛋白的梭形成纤维细胞组成。它们几乎总是无内分泌活性，很少与激素分泌相关。我们在此报告一例60岁的印度女性，表现为绝经后出血。影像学检查和子宫内膜活检显示右卵巢实性肿瘤与增厚的增生期子宫内膜并存，排除了该女性其他高雌激素血症的原因。她接受了全腹子宫切除术及双侧输卵管卵巢切除术。组织病理学显示右卵巢细胞性纤维瘤及增生期子宫内膜，伴有增生灶但无异型性。
