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新生儿早期脑膜炎奈瑟菌致多发性脑脓肿:病例报告及文献复习

Neisseria Meningitidis Causing Multiple Cerebral Abscesses in Early Neonatal Period: Case Report and Review of Literature.

作者信息

Basani Laxman, Aepala Roja

机构信息

Neonatologist and Director Newborn Care Centre, Dolphin Children's Hospital, Hyderabad, Telangana, India.

Paediatric Consultant, Newborn Care Centre, Dolphin Children's Hospital, Hyderabad, Telangana, India.

出版信息

J Clin Diagn Res. 2017 Jul;11(7):SD01-SD03. doi: 10.7860/JCDR/2017/25284.10151. Epub 2017 Jul 1.

Abstract

is a rare cause of meningitis and septicemia in neonates. There are few published case reports of neonatal meningococcal meningitis complicated by subdural empyema, cerebral abscess and hydrocephalus. Few cases of neonatal meningococcal meningitis have been reported in the literature with none of them having the complication of multiple cerebral abscesses in early neonatal period (<seven days of life). We report a case of meningococcal meningitis with multiple cerebral abscesses which presented on fifth day of life and developed hydrocephalus at five weeks of life requiring a Ventriculo Peritoneal (VP) shunt. To the best of our knowledge, this is the first documented case of neonatal meningococcal meningitis with multiple cerebral abscesses.

摘要

是新生儿脑膜炎和败血症的罕见病因。关于新生儿脑膜炎球菌性脑膜炎并发硬膜下积脓、脑脓肿和脑积水的病例报告很少。文献中报道的新生儿脑膜炎球菌性脑膜炎病例很少,且在新生儿早期(出生后<7天)均无多发性脑脓肿并发症。我们报告一例出生后第5天出现的伴有多发性脑脓肿的脑膜炎球菌性脑膜炎病例,出生后5周出现脑积水,需要进行脑室腹腔(VP)分流术。据我们所知,这是首例有记录的伴有多发性脑脓肿的新生儿脑膜炎球菌性脑膜炎病例。

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本文引用的文献

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[Neonatal meningococcal disease].[新生儿脑膜炎球菌病]
An Pediatr (Barc). 2011 Sep;75(3):213-5. doi: 10.1016/j.anpedi.2011.04.010. Epub 2011 Jun 14.
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Neonatal Bacterial Meningitis: 444 Cases in 7 Years.新生儿细菌性脑膜炎:7 年内 444 例。
Pediatr Infect Dis J. 2011 Mar;30(3):212-7. doi: 10.1097/inf.0b013e3181fab1e7.
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Neonatal intrauterine infection with Neisseria meningitidis B.新生儿B群脑膜炎奈瑟菌宫内感染
Clin Pediatr (Phila). 2010 Apr;49(4):388-90. doi: 10.1177/0009922809352376. Epub 2010 Jan 28.

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